Results 121 to 130 of about 156,857 (312)

Computation of Zolotarev Rational Functions

SIAM Journal on Scientific Computing
An algorithm is presented to compute Zolotarev rational functions, that is, rational functions $r_n^*$ of a given degree that are as small as possible on one set $E\subseteq\complex\cup\{\infty\}$ relative to their size on another set $F\subseteq\complex\cup\{\infty\}$ (the third Zolotarev problem).
Lloyd N. Trefethen, Heather D. Wilber
openaire   +3 more sources

A Rational Approximant for the Digamma Function [PDF]

Numerical Algorithms, 2003
Power series representations for special functions are computationally satisfactory only in the vicinity of the expansion point. Thus, it is an obvious idea to use instead Padé approximants or other rational functions constructed from sequence transformations.
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Rational Arithmetic Mathematica Functions to Evaluate the Two-Sided One Sample K-S Cumulative Sampling Distribution [PDF]

One of the most widely used goodness-of-fit tests is the two-sided one sample Kolmogorov-Smirnov (K-S) test which has been implemented by many computer statistical software packages.
J. Randall Brown, Milton E. Harvey
core   +1 more source

On Multivariate Rational Function Decomposition

Journal of Symbolic Computation, 2002
The authors discuss several notions of decomposition for multivariate rational functions, and they present algorithms for decomposing multivariate rational functions over an arbitrary field. They also provide a very efficient method to decide if a unirational field has transcendence degree one, and in the affirmative case to compute the generator.
Jaime Gutierrez 0001, Rosario Rubio San Miguel, David Sevilla   +2 more
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Error estimation in the numerical solution of rational functions

Journal of Applied Sciences and Environmental Management, 2005
In this paper, two methods are described for obtaining estimates of the error of rational functions the Pade\'s and Meahly\'s methods of approximation were used and it was discovered that Maehly\'s proved more accurate than the Pade\'s method.
FO Akinpelu, AA Adetunde, EO Omidiora
doaj   +1 more source

On invariant rational functions under rational transformations

Selecta Mathematica
Let $X$ be an algebraic variety equipped with a dominant rational self-map $ϕ:X\to X$. A new quantity measuring the interaction of $(X,ϕ)$ with trivial dynamical systems is introduced; the stabilised algebraic dimension of $(X,ϕ)$ captures the maximum number of new algebraically independent invariant rational functions on the cartesian product of $(X ...
Bell, Jason, Moosa, Rahim, Satriano, Matthew   +2 more
openaire   +3 more sources