Results 131 to 140 of about 156,857 (312)
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
AxiomsThe iterations of general linear rational functions are investigated. The explicit formulas of iterations are derived for all possible parameters. This allows for an explanation of the global dynamics of linear rational functions. A unification method is
Michal Fečkan
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
A revealed preference analysis of the rational addiction model [PDF]
We provide a revealed preference analysis of the rational addiction model. The revealed preference approach avoids the need to impose an, a priori unverifiable, functional form on the underlying utility function.
Ewout VERRIEST, Thomas DEMUYNCK
core +3 more sources
Plea for Diagonals and Telescopers of Rational Functions
UniverseThis paper is a plea for diagonals and telescopers of rational or algebraic functions using creative telescoping, using a computer algebra experimental mathematics learn-by-examples approach. We show that diagonals of rational functions (and this is also
Saoud Hassani +2 more
doaj +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Factorization of rational six vertex model partition functions
Nuclear Physics BWe show factorization formulas for a class of partition functions of rational six vertex model. First we show factorization formulas for partition functions under triangular boundary.
Kohei Motegi
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The Finite Discrete KP Hierarchy and the Rational Functions
Discrete Dynamics in Nature and Society, 2008 The set of all rational functions with any fixed denominator that simultaneously nullify in the infinite point is parametrized by means of a well-known integrable system: a finite dimensional version of the discrete KP hierarchy.
Raúl Felipe, Nancy López
doaj +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source