Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman +7 more
wiley +1 more source
Associations of health literacy with rational drug use awareness and sleep hygiene in older adults: a cross-sectional study. [PDF]
Ayan FS, Elki̇n N.
europepmc +1 more source
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
A fourth-order exponential time differencing scheme with real and distinct poles rational approximation for solving non-linear reaction-diffusion systems. [PDF]
Attipoe WK +2 more
europepmc +1 more source
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Predicting Solubility Enhancement of <i>Trans</i>-Resveratrol and Hesperetin in Binary Solvent Mixtures Using New Hansen Parameters. [PDF]
Montenegro I +3 more
europepmc +1 more source
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph +11 more
wiley +1 more source
Designing a rational approach for the assessment of peripheral blood lymphocytosis in the acute care setting. [PDF]
Yin C, Reyes J, Walker B.
europepmc +1 more source
Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best +5 more
wiley +1 more source
Application of quick group search optimizer with passive congregation algorithm in cable force optimization of completed bridge of cable-stayed bridge. [PDF]
Qin G, Wang L, Wu Z, Zeng T, Wang H.
europepmc +1 more source

