Results 71 to 80 of about 9,722,579 (330)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Towards a More General Type of Univariate Constrained Interpolation With Fractal Splines

open access: yes, 2015
Recently, in [Electronic Transaction on Numerical Analysis, 41 (2014), pp. 420-442] authors introduced a new class of rational cubic fractal interpolation functions with linear denominators via fractal perturbation of traditional nonrecursive rational ...
Chand, A. K. B.   +2 more
core   +1 more source

Rational two-parameter families of spheres and rational offset surfaces

open access: yesJournal of Symbolic Computation, 2010
A surface in \(\mathbb R^3\) is called PN (Pythagorean normal) if it admits a parametrization in terms of rational functions so that its Gauss map is rational as well. A sphere congruence, given in terms of the Laguerre geometric representation \((u,v)\mapsto(m,r)(u,v)\in\mathbb R^{3,1}\), is called an MOS surface if its induced area form can be ...
openaire   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

The determination of derivative parameters for a monotonic rational quadratic interpolant [PDF]

open access: yes, 1984
Explicit formulae are developed for determining the derivative parameters of a monotonic interpolation method of Gregory and Delbourgo (1982)
Delbourgo, A, Gregory, JA
core  

A uniform classification of discrete series representations of affine Hecke algebras

open access: yes, 2016
We give a new and independent parameterization of the set of discrete series characters of an affine Hecke algebra $\mathcal{H}_{\mathbf{v}}$, in terms of a canonically defined basis $\mathcal{B}_{gm}$ of a certain lattice of virtual elliptic characters ...
Ciubotaru, Dan, Opdam, Eric
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Optimal Rational Approximations by the Modified Fourier Basis

open access: yesAbstract and Applied Analysis, 2018
We consider convergence acceleration of the modified Fourier expansions by rational trigonometric corrections which lead to modified-trigonometric-rational approximations.
Arnak V. Poghosyan, Tigran K. Bakaryan
doaj   +1 more source

Kombinuotųjų stogo konstrukcijų lenkiamojo strypo racionalus projektavimas/Rational design of flexural rod in combined roof structures

open access: yesJournal of Civil Engineering and Management, 1996
The paper discusses a calculation of rational parameters of main flexural rod used in combined roof structures. Geometrical non-linearity can be discussed separately when the member is subjected either to tension or compression.
Algirdas Juozapaitis
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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