Results 51 to 60 of about 1,231,297 (284)
Homotopy obstructions to rational points [PDF]
In this paper we propose to use a relative variant of the notion of the tale homotopy type of an algebraic variety in order to study the existence of rational points on it. In particular, we use an appropriate notion of homotopy fixed points in order to construct obstructions to the local-global principle.
Harpaz, Yonatan, Schlank, Tomer M.
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AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Neural-Network-Based Curve Fitting Using Totally Positive Rational Bases
This paper proposes a method for learning the process of curve fitting through a general class of totally positive rational bases. The approximation is achieved by finding suitable weights and control points to fit the given set of data points using a ...
Rocio Gonzalez-Diaz +3 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Rational Points on Weighted projective Spaces [PDF]
In this paper,we count the rational points on the weighted projective spaces defined over number fields w.r.t. ``size''. An asymptotic formula which generalizes the result of Schanuel's ``Heights in number fields'' is obtained. Furthermore, we count also
Deng, An-Wen
core
Bounded Rational Points on Curves [PDF]
We establish the sharp estimate <
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Uniformity of rational points [PDF]
Let \(K\) be a number field. A question addressed in this paper is the following: Given a family \(f:X\to B\) of curves defined over \(K\), how does the set of \(K\)-rational points of the fibres vary with \(b\in B\), and in particular, how does its cardinality behave as a function of \(b\)?
Caporaso, Lucia +2 more
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
On the distribution of ramification points in trigonal curves
We study the distribution of the total and ordinary ramification points of a trigonal curve over the intersection of this curve with rational curves on a rational normal scroll.
Cícero F. Carvalho
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q-deformed rational numbers and the 2-Calabi–Yau category of type $A_{2}$
We describe a family of compactifications of the space of Bridgeland stability conditions of a triangulated category, following earlier work by Bapat, Deopurkar and Licata. We particularly consider the case of the 2-Calabi–Yau category of the $A_2$
Asilata Bapat +2 more
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