Results 81 to 90 of about 729,207 (352)
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Deliberately ignoring inequality to avoid rejecting unfair offers
Communications PsychologyWhy do people punish experienced unfairness if it induces costs for both the punisher and punished person(s) without any direct material benefits for the punisher?
Konstantin Offer +3 more
doaj +1 more source
, 2000 Using rationality, like in language theory, we de ne a family of in nite graphs. This family is a strict extension of the context-free graphs of Muller and Schupp, the equational graphs of Courcelle and the pre x recognizable graphs of Caucal. We give basic properties, as well as an internal and an external characterization of these graphs.
openaire +4 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Rationality: a social-epistemology perspective [PDF]
, 2014 Both in philosophy and in psychology, human rationality has traditionally been studied from an "individualistic" perspective. Recently, social epistemologists have drawn attention to the fact that epistemic interactions among agents also give rise to ...
Douven, I +2 more
core +4 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Cobordism invariants of the moduli space of stable pairs
, 2016 For a quasi-projective scheme M which carries a perfect obstruction theory, we construct the virtual cobordism class of M. If M is projective, we prove that the corresponding Chern numbers of the virtual cobordism class are given by integrals of the ...
Shen, Junliang
core +1 more source
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Allocation of scarce resources when rationality is one of them: some consequences of cognitive inequalities for theory and policy [PDF]
"Rationality" is understood in the empirical sense of cognitive abilities of human brains for solving economic problems, and consequently recognized bounded in individually unequal ways.
Pelikan, Pavel
core +1 more source