Results 31 to 40 of about 6,402 (133)
Real‐World Therapeutic Hypothermia for Neonatal HIE: Neurodevelopmental Outcomes and Predictors
Acta Paediatrica, Volume 114, Issue 11, Page 2874-2884, November 2025.ABSTRACT Aim This study assessed neurodevelopmental outcomes in neonates with hypoxic‐ischemic encephalopathy (HIE) treated with therapeutic hypothermia (TH) outside randomised controlled trials (RCTs). It also aimed to identify predictors of outcomes and evaluate TH practices across centres.
Luca Bedetti +23 more
wiley +1 more source
Molecular Ecology, Volume 34, Issue 21, November 2025.ABSTRACT Parasites are expected to hybridise in similar ways to free‐living organisms, although this may be modified by their reduced genome architecture. Recombinant strains and taxa of hybrid origin can be studied in nature where hosts come into secondary contact. Here we apply genome‐wide analysis to parasites from a contact previously characterised
Jan Petružela +9 more
wiley +1 more source
Organ Specificity and Commonality of Epigenetic Aging in Low‐ and High‐Running Capacity Rats
Aging Cell, Volume 24, Issue 8, August 2025.Cardiorespiratory fitness (CRF) is not associated with epigenetic clocks, including newly developed ones. On the other hand, CRF is associated with global methylation profiles and promoter methylation in organ‐specific and organ‐common manner. ABSTRACT Epigenetic drift, which is gradual age‐related changes in DNA methylation patterns, plays a ...
Takuji Kawamura +15 more
wiley +1 more source
Acta Paediatrica, Volume 114, Issue 8, Page 1868-1876, August 2025.ABSTRACT Aim To compare less invasive surfactant administration (LISA) and intubation‐surfactant‐extubation (INSURE) in infants born before 28 weeks gestational age (GA) by the need for mechanical ventilation (MV). Methods LISA was introduced in 2017 in our unit without formal prior LISA‐specific training as an equal alternative to INSURE.
C. Heiring +9 more
wiley +1 more source
Identification of a Novel Gene for Diabetic Traits in Rats, Mice, and Humans [PDF]
, 2014 The genetic basis of type 2 diabetes remains incompletely defined despite the use of multiple genetic strategies. Multiparental populations such as heterogeneous stocks (HS) facilitate gene discovery by allowing fine mapping to only a few megabases ...
Andrae, Jaime Wendt +18 more
core +1 more source
Evolutionary Applications, Volume 18, Issue 8, August 2025.ABSTRACT The United Kingdom aims to dramatically accelerate the establishment of new woodlands by 2050, yet the impact of different afforestation strategies on landscape genetic diversity and resilience remains unclear. This study integrates environmental data, whole‐genome sequencing and phenotypic assessments to compare bioclimatic envelopes, genetic
Guillermo Friis +8 more
wiley +1 more source
The practice and promise of temporal genomics for measuring evolutionary responses to global change
Molecular Ecology Resources, Volume 25, Issue 5, July 2025.Abstract Understanding the evolutionary consequences of anthropogenic change is imperative for estimating long‐term species resilience. While contemporary genomic data can provide us with important insights into recent demographic histories, investigating past change using present genomic data alone has limitations.
René D. Clark +9 more
wiley +1 more source
Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]
, 2015 Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core +1 more source
Epilepsia, Volume 66, Issue 7, Page 2285-2294, July 2025.Abstract Objective This study was undertaken to describe a case series of Brazilian new onset refractory status epilepticus (NORSE) patients and evaluate the sensitivity and specificity of a clinical score to predict cryptogenic etiology (c‐NORSE score) after autoimmune encephalitis (AE) testing.
João Henrique Fregadolli Ferreira +42 more
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 3, June 2025.ABSTRACT Background Deterioration of functional capacity mostly determinates frailty in older patients with cardiovascular disease (CVD). Elucidating the pathophysiological mechanisms of physical frailty is an important goal for improving functional health‐related outcomes. Our objective was the determination of the transcriptomic signature of physical
Omar Baritello +16 more
wiley +1 more source