Results 41 to 50 of about 14,911 (165)

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.
Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley   +1 more source

Creation of a Computational Pipeline to Extract Genes from Quantitative Trait Loci for Diabetes and Obesity [PDF]

, 2015
Type 2 Diabetes is a disease of relative insulin deficiency resulting from a combination of insulin resistance and decreased beta-cell function. Over the past several years, over 60 genes have been identified for Type 2 Diabetes in human genome-wide ...
Fox, Joseph
core   +1 more source

Relative contribution of direct and indirect allorecognition in developing tolerance after liver transplantation [PDF]

, 2008
The interaction of donor passenger leukocytes and host leukocytes in recipient secondary lymphoid tissues during the early posttransplantation period is crucial in directing host immune reactions toward allograft rejection or acceptance.
Akdis, Benichou, Buiting, Cebon, Csencsits, Dai, Demetris, Demetris, Demetris, Fleisch, Ganta, Gould, Heeger, Huitinga, Ichikawa, Josien, Jurcevic, Ko, Konieczny, Lakkis, Larsen, Lechler, Mellor, Munn, Murase, Murase, Murase, Nakao, Neto, Nikolic, Okuda, Rabinovich, Raisanen-Sokolowski, Sawitzki, Sekine, Sims, Slegers, Smith, Starzl, Starzl, Sun, Talmage, Van Rooijen, Van Rooijen, Van Rooijen, Wu, Yagihashi, Yan, Zhang   +48 more
core   +2 more sources

Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in LG/J Mice

Aging Cell, Volume 24, Issue 5, May 2025.
An endochondral differentiation process in the CEPs drives pathologic disc calcification in aging LG/J mice, and NP cell hypertrophic transdifferentiation secondarily contributes. Supplementing drinking water with 80 mM K3Citrate during aging markedly reduced disc calcification, attenuated NP cell transdifferentiation, and mildly improved NP and AF ...
Olivia K. Ottone, Jorge J. Mundo, Boahen N. Kwakye, Amber Slaweski, John A. Collins, Qinglin Wu, Margery A. Connelly, Fatemeh Niaziorimi, Koen van de Wetering, Makarand V. Risbud   +9 more
wiley   +1 more source

A review of Mpox: Biological characteristics, epidemiology, clinical features, diagnosis, treatment, and prevention strategies

Exploration, Volume 5, Issue 2, April 2025.
The monkeypox virus (MPXV) has spread to many countries and caused thousands of infections all over the world. This review comprehensively introduces the biology, epidemiological characteristics of MPXV, and clinical manifestations of Mpox. The approaches for diagnosis, treatment, and prevention are also introduced, aiming to improve the general ...
Lin Jiang, Ailan Xu, Lin Guan, Yong Tang, Guangshuai Chai, Junya Feng, Yueqi Wu, Maochen Li, Chuxie Zhang, Xiaojing Liu, Xiaolong Xu, Qingquan Liu, Lihua Song, Yigang Tong, Renald Blundell, Huahao Fan   +15 more
wiley   +1 more source

Genetic Loci Influencing Cue‐Reactivity in Heterogeneous Stock Rats

Genes, Brain and Behavior, Volume 24, Issue 2, April 2025.
A genome‐wide association study characterizing individual differences in cue‐reactivity (sign‐tracking; A) identifies multiple genetic loci, particularly on chromosomes 1 and 18 (B). Multiple candidate genes in these regions were identified, including those with known psychiatric relevance (e.g., Tenm4; C) and novel candidates with heritable ...
Christopher P. King, Apurva S. Chitre, Joel D. Leal‐Gutiérrez, Jordan A. Tripi, Alesa H. Netzley, Aidan P. Horvath, Alexander C. Lamparelli, Anthony George, Connor Martin, Celine L. St. Pierre, Thiago Missfeldt Sanches, Hannah V. Bimschleger, Jianjun Gao, Riyan Cheng, Khai‐Minh Nguyen, Katie L. Holl, Oksana Polesskaya, Keita Ishiwari, Hao Chen, Terry E. Robinson, Shelly B. Flagel, Leah C. Solberg Woods, Abraham A. Palmer, Paul J. Meyer   +23 more
wiley   +1 more source

Identification of a Novel Gene for Diabetic Traits in Rats, Mice, and Humans [PDF]

, 2014
The genetic basis of type 2 diabetes remains incompletely defined despite the use of multiple genetic strategies. Multiparental populations such as heterogeneous stocks (HS) facilitate gene discovery by allowing fine mapping to only a few megabases ...
Andrae, Jaime Wendt, Galione, Antony, He, Hong, Hessner, Martin, Hoffmann, Raymond G., Holl, Katie, Jacob, Howard, Jia, Shuang, Kaldunski, Mary, Li, Shun-Hua, Meigs, James, Parrington, John, Ruas da Silva, Margarida, Simpson, Pippa, Solberg Woods, Leah C., Stoddard, Alex, Tsaih, Shirng-Wern, Tschannen, Michael, Wiederhold, Andrew   +18 more
core   +1 more source

Jan and mini‐Jan, a model system for potato functional genomics

Plant Biotechnology Journal, Volume 23, Issue 4, Page 1243-1256, April 2025.
Summary Potato (Solanum tuberosum) is the third‐most important food crop in the world. Although the potato genome has been fully sequenced, functional genomics research of potato lags behind that of other major food crops, largely due to the lack of a model experimental potato line.
Haoyang Xin, Luke W. Strickland, John P. Hamilton, Jacob K. Trusky, Chao Fang, Nathaniel M. Butler, David S. Douches, C. Robin Buell, Jiming Jiang   +8 more
wiley   +1 more source

FK506 suppression of heart and liver allograft rejection: II: The induction of graft acceptance in rats [PDF]

, 1990
Lewis recipients of orthotopic ACI livers had permanent graft acceptance induced with 3 doses of i.m. FK506 in the early postoperative period. They were studied 100 and 300 days posttransplantation.
Cramer, DV, Dong-Goo, K, Fung, J, Murase, N, Starzl, TE, Todo, S   +5 more
core   +1 more source

A High‐Quality Reference Genome and Comparative Genomics of the Widely Farmed Banded Cricket (Gryllodes sigillatus) Identifies Selective Breeding Targets

Ecology and Evolution, Volume 15, Issue 3, March 2025.
ABSTRACT Farmed insects have gained attention as an alternative, sustainable source of protein with a lower carbon footprint than traditional livestock. We present a high‐quality reference genome for one of the most commonly farmed insects, the banded cricket Gryllodes sigillatus. In addition to its agricultural importance, G.
Shangzhe Zhang, Kristin R. Duffield, Bert Foquet, Jose L. Ramirez, Ben M. Sadd, Scott K. Sakaluk, John Hunt, Nathan W. Bailey   +7 more
wiley   +1 more source