Results 11 to 20 of about 22,161 (167)
Photoperiodic Effects on Seasonal Physiology, Reproductive Status and Hypothalamic Gene Expression in Young Male F344 Rats [PDF]
Journal of neuroendocrinology, 2014 yesSeasonal or photoperiodically sensitive animals respond to altered day length with changes in physiology (growth, food intake and reproductive status) and behaviour to adapt to predictable yearly changes in the climate.
Barrett +44 more
core +3 more sources
Frontiers in Neuroscience, 2018 The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark symptoms of human adult-onset HD.
Anne-Christine Plank +11 more
doaj +2 more sources
The FASEB Journal, 2012 Genetic background has a major influence on the severity of renovascular disease. Previously we showed that Lewis rats with inducible hypertension caused by transgenic renin expression have lower blood pressure, higher renal plasma flow (RPF) and glomerular filtration rate (GFR) and are relatively protected from hypertensive renal microvascular injury ...
John J. Mullins +3 more
openaire +3 more sources
Japanese Journal of Oral & Maxillofacial Surgery, 1991 A number of transplantable animal models of osteosarcoma have been developed so far, but the available strains of the rat that keep their bone-forming ability through many serial transplantations are limited both in the number of strains and their applicability.
S. Uchiyama
openaire +4 more sources
Effects of Neonatal Handling on Play and Anxiety in F344 and Lewis Rats
Developmental Psychobiology, 2018 Play is an important part of normal childhood development and seen in many mammals, including rats. To better understand the interplay between genotype and postnatal experiences, the effects of neonatal handling on play were assessed in Lewis (LEW) and ...
Siviy, Stephen M.
core +2 more sources
Comparison of Thermal and Mechanical Pain Testing Modalities in Sprague Dawley and Fischer 344 Rats (<i>Rattus norvegicus</i>). [PDF]
Comp MedWhile rodents are used extensively for studying pain, there is a lack of reported direct comparisons of thermal and mechanical pain testing methods in rats of different genetic backgrounds.
McNew JF +3 more
europepmc +2 more sources
Whole exome and transcript profiling of liver following aflatoxin B1 exposure in rats
Journal of Applied Toxicology, Volume 43, Issue 9, Page 1293-1305, September 2023., 2023 Abstract We recently developed a rat whole exome sequencing (WES) panel and used it to evaluate early somatic mutations in archival liver tissues from F344/N rats exposed to the hepatocarcinogen, Aflatoxin B1 (AFB1), a widely studied, potent mutagen and hepatocarcinogen associated with hepatocellular carcinoma (HCC).
Julie F. Foley +10 more
wiley +1 more source
Advanced models for respiratory disease and drug studies
Medicinal Research Reviews, Volume 43, Issue 5, Page 1470-1503, September 2023., 2023 Abstract The global burden of respiratory diseases is enormous, with many millions of people suffering and dying prematurely every year. The global COVID‐19 pandemic witnessed recently, along with increased air pollution and wildfire events, increases the urgency of identifying the most effective therapeutic measures to combat these diseases even ...
Jesus Shrestha +8 more
wiley +1 more source
Cell Proliferation, Volume 56, Issue 5, May 2023., 2023 We established a novel inducible haematopoietic cell‐depleting mouse model and tested the feasibility of using chimeric complementation to regenerate HSCs and their progeny cells. Large populations of syngeneic and major histocompatibility‐mismatched haematopoietic cells were successfully regenerated by this model.
Weiyun Cao +7 more
wiley +1 more source