Results 21 to 30 of about 8,257 (145)

Lymphoma caused by intestinal microbiota. [PDF]

, 2014
The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core   +2 more sources

Early Alterations in Operant Performance and Prominent Huntingtin Aggregation in a Congenic F344 Rat Line of the Classical CAGn51trunc Model of Huntington Disease

Frontiers in Neuroscience, 2018
The transgenic rat model of Huntington disease expressing a fragment of mutant HTT (tgHD rat) has been thoroughly characterized and reproduces hallmark symptoms of human adult-onset HD.
Anne-Christine Plank, Fabio Canneva, Kerstin A. Raber, Yvonne K. Urbach, Julia Dobner, Maja Puchades, Jan G. Bjaalie, Clarissa Gillmann, Tobias Bäuerle, Olaf Riess, Hoa H. P. Nguyen, Stephan von Hörsten   +11 more
doaj   +1 more source

Strain specific effects of low level lead exposure on associative learning and memory in rats. [PDF]

, 2017
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impairs the normal development of numerous cognitive and neurobehavioral processes.
Schneider, J. S., Verma, Megha
core   +2 more sources

Salivary α-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells and human breast cancer cells

Journal of Experimental & Clinical Cancer Research, 2011
Background Breast cancer is one of the most diagnosed cancers in females, frequently with fatal outcome, so that new strategies for modulating cell proliferation in the mammary tissue are urgently needed.
Bertram Catharina, Hass Ralf, Fedrowitz Maren, Löscher Wolfgang   +3 more
doaj   +1 more source

Pressure–natriuretic and hemodynamic adjustments to chronic ACE inhibition in inbred F344 and Lewis rat strains

The FASEB Journal, 2012
Genetic background has a major influence on the severity of renovascular disease. Previously we showed that Lewis rats with inducible hypertension caused by transgenic renin expression have lower blood pressure, higher renal plasma flow (RPF) and glomerular filtration rate (GFR) and are relatively protected from hypertensive renal microvascular injury ...
John J. Mullins, Matthew A. Bailey, Christopher J. Kenyon, Robert I. Menzies   +3 more
openaire   +2 more sources

Photoperiodic Effects on Seasonal Physiology, Reproductive Status and Hypothalamic Gene Expression in Young Male F344 Rats [PDF]

, 2014
yesSeasonal or photoperiodically sensitive animals respond to altered day length with changes in physiology (growth, food intake and reproductive status) and behaviour to adapt to predictable yearly changes in the climate.
Barrett, Barrett, Braulke, Dardente, Francisco, Hanon, Hanon, Hau, Heideman, Heideman, Heideman, Helfer, Helfer, Herwig, Herwig, Hoffmann, Inestrosa, Klingenspor, Krol, Lobley, Nakane, Nakao, Nelson, Ono, Otsuka, Petri, Prendergast, Revel, Ross, Ross, Ross, Ross, Rousseau, Scherbarth, Seroka, Shaw, Shearer, Shoemaker, Togo, Tsai, Wallen, Wallen, Watanabe, Yasuo, Yoshimura   +44 more
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Efficient gene targeting by homologous recombination in rat embryonic stem cells.

PLoS ONE, 2010
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombination.
Stephen Meek, Mia Buehr, Linda Sutherland, Alison Thomson, John J Mullins, Andrew J Smith, Tom Burdon   +6 more
doaj   +1 more source

Fine mapping of bone structure and strength QTLs in heterogeneous stock rat [PDF]

, 2015
We previously demonstrated that skeletal structure and strength phenotypes vary considerably in heterogeneous stock (HS) rats. These phenotypes were found to be strongly heritable, suggesting that the HS rat model represents a unique genetic resource for
Alam, Imranul, Baud, Amelie, Blázquez, Gloria, Cañete, Toni, Diez, Margarita, Díaz-Morán, Sira, Econs, Michael J., Fernández-Teruel, Alberto, Foroud, Tatiana, Johannesson, Martina, Koller, Daniel L., López-Aumatell, Regina, Martínez-Membrives, Esther, Mont-Cardona, Carme, Olsson, Tomas, Stridh, Pernilla, Tobeña, Adolf   +16 more
core   +1 more source

Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon

BMC Gastroenterology, 2009
Background Blueberries may lower relative risk for cancers of the gastrointestinal tract. Previous work indicated an inhibitory effect of consumed blueberry (BB) on formation of aberrant crypt foci (ACF) in colons of male Fisher F344 rats (inbred strain).
Wu Xianli, Frank Julie A, Simmen Frank A, Xiao Rijin, Hennings Leah J, Prior Ronald L   +5 more
doaj   +1 more source

Rat Strain Ontology: structured controlled vocabulary designed to facilitate access to strain data at RGD [PDF]

, 2013
BACKGROUND: The Rat Genome Database (RGD) ( http://rgd.mcw.edu/) is the premier site for comprehensive data on the different strains of the laboratory rat (Rattus norvegicus).
Diane H Munzenmaier, Elizabeth A Worthey, Howard J Jacob, Mary Shimoyama, Melinda R Dwinell, Rajni Nigam   +5 more
core   +2 more sources