Results 21 to 30 of about 22,161 (167)

Revisiting the testicular toxicity of cyanide: Assessment of the new and existing literature

Birth Defects Research, Volume 115, Issue 7, Page 687-709, April 15, 2023., 2023
Abstract Background Based on new testing, we re‐assess U.S. EPA and California OEHHA conclusions regarding male reproductive toxicity associated with cyanide exposure. Methods Literature identified by ATSDR, ECETOC and EPA was complemented by studies conducted after 2006. Relevant studies were scored for quality using ToxRTool. Results Eleven pertinent
Amy Lavin Williams, John M. DeSesso
wiley   +1 more source

Lewis, Fischer 344, and Sprague-Dawley rats display differences in lipid peroxidation, motor recovery, and rubrospinal tract preservation after spinal cord injury.

Frontiers in Neurology, 2015
The rat is the most common animal model for the preclinical validation of neuroprotective therapies in spinal cord injury (SCI). Lipid peroxidation (LP) is a hallmark of the damage triggered after SCI.
Humberto eMestre, Manuel eRamirez, Elisa eGarcia, Elisa eGarcia, Susana eMartiñón, Yolanda eCruz, Maria G. Campos, Antonio eIbarra, Antonio eIbarra   +8 more
doaj   +1 more source

Mouse models of colorectal cancer. [PDF]

, 2011
Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip, Tong, Yunguang, Yang, Wancai   +2 more
core   +2 more sources

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Journal, Volume 21, Issue 4, April 2023., 2023
Abstract In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the risks to public health from the presence of BPA in foodstuffs and to establish a tolerable daily intake (TDI). For this re‐evaluation, a pre‐established protocol was
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Claude Lambré, José Manuel Barat Baviera, Claudia Bolognesi, Andrew Chesson, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Marcel Mengelers, Alicja Mortensen, Gilles Rivière, Vittorio Silano (until 21 December 2020†), Inger‐Lise Steffensen, Christina Tlustos, Laurence Vernis, Holger Zorn, Monika Batke, Margherita Bignami, Emanuela Corsini, Rex FitzGerald, Ursula Gundert‐Remy, Thorhallur Halldorsson, Andrew Hart, Evangelia Ntzani, Eugenio Scanziani, Henri Schroeder, Beate Ulbrich, Dina Waalkens‐Berendsen, Detlef Woelfle, Zainab Al Harraq, Katleen Baert, Maria Carfì, Anna F Castoldi, Cristina Croera, Henk Van Loveren   +37 more
wiley   +1 more source

The influence of cervical and thoracic lymphadenectomy on corneal allograft rejection in inbred rats [PDF]

, 2011
Aim To investigate the site of alloantigen presentation in the rat following orthotopic corneal transplantation. Methods Adult inbred Fischer 344 rats received penetrating corneal allografts from inbred Wistar Furth donors (n¼17), without lymphadenectomy.
Brereton, Helen Mary, Brice, Sarah L, Coster, Douglas John, Kirk, Kirsty, Williams, Keryn Anne   +4 more
core   +1 more source

Lymphoma caused by intestinal microbiota. [PDF]

, 2014
The intestinal microbiota and gut immune system must constantly communicate to maintain a balance between tolerance and activation: on the one hand, our immune system should protect us from pathogenic microbes and on the other hand, most of the millions ...
Schiestl, Robert H, Yamamoto, Mitsuko L
core   +2 more sources

Strain specific effects of low level lead exposure on associative learning and memory in rats. [PDF]

, 2017
Exposure to lead (Pb) remains a significant public health concern. Lead exposure in early life impairs the normal development of numerous cognitive and neurobehavioral processes.
Schneider, J. S., Verma, Megha
core   +2 more sources

Salivary α-amylase exhibits antiproliferative effects in primary cell cultures of rat mammary epithelial cells and human breast cancer cells

Journal of Experimental & Clinical Cancer Research, 2011
Background Breast cancer is one of the most diagnosed cancers in females, frequently with fatal outcome, so that new strategies for modulating cell proliferation in the mammary tissue are urgently needed.
Bertram Catharina, Hass Ralf, Fedrowitz Maren, Löscher Wolfgang   +3 more
doaj   +1 more source

Efficient gene targeting by homologous recombination in rat embryonic stem cells.

PLoS ONE, 2010
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombination.
Stephen Meek, Mia Buehr, Linda Sutherland, Alison Thomson, John J Mullins, Andrew J Smith, Tom Burdon   +6 more
doaj   +1 more source

Fine mapping of bone structure and strength QTLs in heterogeneous stock rat [PDF]

, 2015
We previously demonstrated that skeletal structure and strength phenotypes vary considerably in heterogeneous stock (HS) rats. These phenotypes were found to be strongly heritable, suggesting that the HS rat model represents a unique genetic resource for
Alam, Imranul, Baud, Amelie, Blázquez, Gloria, Cañete, Toni, Diez, Margarita, Díaz-Morán, Sira, Econs, Michael J., Fernández-Teruel, Alberto, Foroud, Tatiana, Johannesson, Martina, Koller, Daniel L., López-Aumatell, Regina, Martínez-Membrives, Esther, Mont-Cardona, Carme, Olsson, Tomas, Stridh, Pernilla, Tobeña, Adolf   +16 more
core   +1 more source