Results 51 to 60 of about 22,238 (163)

Cerebellar output controls generalized spike-and-wave discharge occurence [PDF]

open access: yes, 2015
© 2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (CC BY-NC-ND 4.0)
Alva, Parimala   +15 more
core   +5 more sources

Genetic background and sex influence somatosensory sensitivity and oxycodone analgesia in the Hybrid Rat Diversity Panel

open access: yesGenes, Brain and Behavior, Volume 23, Issue 2, April 2024.
Using the Hybrid Rat Diversity Panel, we demonstrated that sex and genetic background confer differences in mechanical sensitivity, thermal sensitivity, and oxycodone‐induced analgesia. Created with BioRender.com. Abstract Opioid use disorder (OUD) is an ongoing public health concern in the United States, and relatively little work has addressed how ...
Eamonn P. Duffy   +7 more
wiley   +1 more source

Long term methionine restriction: Influence on gut microbiome and metabolic characteristics

open access: yesAging Cell, Volume 23, Issue 3, March 2024.
A long‐term Methionine restriction diet in mice had less impact on the gut microbiome compared to short‐term feeding, with aging showing more significant effects on bacterial taxa. Specific dietary changes in bacterial taxa occurred at 1 or 18‐week intervals, while consistent age‐related changes were noted in certain taxa across both diet groups ...
Akash Nagarajan   +3 more
wiley   +1 more source

Endogenous N-nitroso compounds, and their precursors, present in bacon, do not initiate or promote aberrant crypt foci in the colon of rats [PDF]

open access: yes, 2000
Processed meat intake is associated with increased risk of colorectal cancer. This association may be explained by the endogenous formation of N-nitroso compounds (NOC).
Corpet, Denis E.   +4 more
core   +1 more source

Exploring the Impact of Biological Agents on Protecting Against Experimental Periodontitis: A Systematic Review of Animal‐Based Studies

open access: yesBioMed Research International, Volume 2024, Issue 1, 2024.
Aim: This systematic review was aimed at addressing the focused question: What is the protective potential of biological agents against alveolar bone resorption during the progression of experimental periodontitis (EP)? Material and Methods: The study protocol was registered in the Open Science Framework database (doi:10.17605/OSF.IO/3P2HY).
Gabriela Ezequiel Oliveira   +9 more
wiley   +1 more source

Positional identification and functional analysis of genes regulating autoimmune arthritis [PDF]

open access: yes, 2016
The major histocompatibility complex (MHC) is the most gene-dense and polymorphic region in the human genome with strong associations to many autoimmune disorders, including rheumatoid arthritis (RA).
Yau, Anthony Chun Yeung
core   +1 more source

A Brain Motivated to Play: Insights into the Neurobiology of Playfulness

open access: yes, 2016
Play is an important part of normal childhood development and is seen in varied forms among many mammals. While not indispensable to normal development, playful social experiences as juveniles may provide an opportunity to develop flexible behavioural ...
Siviy, Stephen M.
core   +1 more source

Effect of Gsk3 inhibitor CHIR99021 on aneuploidy levels in rat embryonic stem cells [PDF]

open access: yes, 2014
Germline competent embryonic stem (ES) cells can serve as a tool to create genetically engineered rat strains used to elucidate gene function or provide disease models.
Anagha S. Bock   +2 more
core   +1 more source

Differential Behavioral Responses to\ud Cocaethylene of Long-Evans and\ud Sprague-Dawley Rats: Role of Serotonin [PDF]

open access: yes, 1997
Cocaethylene is a neuroactive metabolite derived from the concurrent consumption of cocaine and ethanol. The effects of cocaethylene on locomotor activity, stereotypy, and rearing in Long-Evans and Sprague-Dawley rats were compared.A single cocaine ...
Horowitz, Dr. J.M.   +2 more
core  

Genomes and phenomes of a population of outbred rats and its progenitors [PDF]

open access: yes, 2014
Finding genetic variants that contribute to phenotypic variation is one of the main challenges of modern genetics. We used an outbred population of rats (Heterogeneous Stock, HS) in a combined sequence-based and genetic mapping analysis to identify ...
  +5 more
core   +3 more sources

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