Positional identification of variants of Adamts16 linked to inherited hypertension [PDF]
, 2017 A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665.
Achinike, Ovokeraye H. +25 more
core
Reduced Levels of mGlu2 Receptors within the Prelimbic Cortex Are Not Associated with Elevated Glutamate Transmission or High Alcohol Drinking [PDF]
, 2017 Background A Grm2 cys407* stop codon mutation, which results in a loss of the metabotropic glutamate 2 (mGlu2) receptor protein, was identified as being associated with high alcohol drinking by alcohol-preferring (P) rats.
Bell, Richard L. +5 more
core +1 more source
Susceptibility of partially desalivated rats to erosive tooth wear by calcium-supplemented beverages [PDF]
, 2017 Objectives To investigate the susceptibility of partially desalivated rats to erosive tooth wear (ETW); the anti-erosive effect of a calcium-supplemented beverage; and the quantification of ETW by microcomputed tomography (micro-CT).
Aldosari, Mohammad +5 more
core +1 more source
Reduced body mass, food intake, and testis size in response to short photoperiod in adult F344 rats
BMC Physiology, 2002 BackgroundAlthough laboratory rats are often considered classic nonseasonal breeders, peripubertal rats of two inbred strains, F344 and BN, have both reproductive and nonreproductive responses to short photoperiods. Unmanipulated adult rats have not been
M. Shoemaker +2 more
semanticscholar +1 more source
K-ras mutations are frequent in pulmonary squamous cell carcinomas but not in adenocarcinomas of WBN/Kob rats induced by N-nitrosobis(2-oxopropyl)amine [PDF]
, 2017 Pulmonary carcinomas induced by N-nitrosobis(2-oxopropyl) amine (BOP) in WBN/Kob rats were screened for point mutations in the K-ras protooncogene. Exons 1 and 2 were polymerase chain reaction amplified from paraffin-embedded sections, followed by direct
Furukawa, Fumio +3 more
core
Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection [PDF]
, 2014 We previously found that estrogen exerts a novel protective effect on mitochondria in brain vasculature. Here we demonstrate in rat cerebral blood vessels that 17beta-estradiol (estrogen), both in vivo and ex vivo, affects key transcriptional ...
C. Stirone +4 more
core +4 more sources
Stability of small non-coding RNA reference gene expression in the rat retina during exposure to cyclic hyperoxia [PDF]
, 2013 Purpose: Oxygen-induced retinopathy (OIR) is a robust animal model of human retinopathy of prematurity that readily allows changes in retinal gene and microRNA (miRNA) expression in response to fluctuations in oxygen levels to be studied.
Brereton, Helen Mary +3 more
core
Impact of aging on the auditory system and related cognitive functions: A narrative review [PDF]
, 2018 Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects approximately one-third of the world’s population. The peripheral and central hearing alterations associated with age-related hearing loss have a profound impact on ...
Friedland, Peter L +3 more
core +3 more sources