Refinement and Reduction Value of Aspen Furniture and Restricted Feeding of Rats in Conventional Cages [PDF]
, 2012 This study evaluated the impact of aspen furniture on cardiovascular parameters, locomotor activity (LA) and faecal welfare indicators in rats. A total of 12 BN and 12 F344 male rats were group housed (n=3) in conventional cages. In this crossover study,
Hau, Jann +5 more
core +3 more sources
Effects of Neonatal Handling on Play and Anxiety in F344 and Lewis Rats
, 2018 Play is an important part of normal childhood development and seen in many mammals, including rats. To better understand the interplay between genotype and postnatal experiences, the effects of neonatal handling on play were assessed in Lewis (LEW) and ...
Siviy, Stephen M.
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The amphetamine sensitization model of schizophrenia: relevance beyond psychotic symptoms? [PDF]
, 2018 Rationale: A sensitized dopamine system may be linked to the genesis of psychotic symptoms in schizophrenia. Following withdrawal from amphetamine exposures, psychotic-like traits have been robustly demonstrated, but the presence of cognitive/mnemonic ...
Feldon, Joram +3 more
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Trichloroethylene-induced formic aciduria: effect of dose, sex and strain of rat. [PDF]
The industrial solvent trichloroethylene (TCE) has been reported to increase the excretion of formic acid in the urine of male Fischer 344 (F-344) rats following large oral doses.
Evans, AR, Lock, EA, Yaqoob, N
core
Use of a multistrain assay could improve the NTP carcinogenesis bioassay. [PDF]
, 1995 There are often large strain differences in the response of laboratory animals to toxic chemicals and carcinogens, with some strains being totally resistant to dose levels that cause acute toxicity and/or cancer in other strains.
Festing, M F
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Slc:Wistar outbred rats show close genetic similarity with F344 inbred rats
Slc:Wistar outbred rats show close genetic similarity with F344 inbred ratsAlthough Slc:Wistar rats are used widely in biomedical research as outbred rats, close similarities in growth curves, survival rates, and immunological and biochemical phenotypes have been reported between Slc:Wistar and F344 inbred rats. We reported previously that nine genetic variations that were fixed in Slc:Wistar rats had identical genotypes in ...
openaire
Delay Discounting in Lewis and Fischer 344 Rats: Implications for the Use of an Adjusting-amount Procedure to Detect Between-strain Differences [PDF]
, 2010 Strain-related behavioral differences may facilitate investigation of the genetic and neurochemical determinants of delay discounting. Previous researchers report that Lewis rats make more impulsive choices than Fischer 344 rats, although the size of ...
Stein, Jeff S.
core
Permissive immunosuppression facilitates the expansion of ex vivo administered regulatory T cells in the lung allograft. [PDF]
Sci RepTakahagi A +10 more
europepmc +1 more source
Establishing the hybrid rat diversity program: a resource for dissecting complex traits. [PDF]
Mamm GenomeDwinell MR +12 more
europepmc +1 more source
Photoperiod-Dependent Effects of Phenolic-Enriched Fruit Extracts on Postprandial Triacylglyceride Levels and Acute Inflammatory Responses in F344 Rats. [PDF]
Mol Nutr Food ResManocchio F +6 more
europepmc +1 more source