Positional identification of variants of Adamts16 linked to inherited hypertension [PDF]
A previously reported blood pressure (BP) quantitative trait locus on rat Chromosome 1 was isolated in a short congenic segment spanning 804.6 kb. The 804.6 kb region contained only two genes, LOC306664 and LOC306665.
Achinike, Ovokeraye H.+25 more
core
FK506 suppression of heart and liver allograft rejection: II: The induction of graft acceptance in rats [PDF]
Lewis recipients of orthotopic ACI livers had permanent graft acceptance induced with 3 doses of i.m. FK506 in the early postoperative period. They were studied 100 and 300 days posttransplantation.
Cramer, DV+5 more
core +1 more source
Nervous system‐related tropism of SARS‐CoV‐2 and autoimmunity in COVID‐19 infection
This review summarizes the current knowledge regarding neurotropism and emerging immune responses in SARS‐CoV‐2 infection. There are direct and indirect effects on the nervous system by SARS‐CoV‐2 infection. Presently, vaccination against SARS‐CoV‐2 is the most effective way of preventing SARS‐CoV‐2 infection of the nervous system. Abstract The effects
Robert Weissert
wiley +1 more source
Upregulation of Transglutaminase andε(γ-Glutamyl)-Lysine in the Fisher-Lewis Rat Model of Chronic Allograft Nephropathy [PDF]
Background. Tissue transglutaminase (TG2), a cross-linking enzyme, modulates deposition of extracellular matrix protein in renal fibrosis. This study aimed to examine TG2 and its cross-link product ε(γ-glutamyl)-lysine in the Fisher-Lewis rat renal ...
Butt, Imran+7 more
core +3 more sources
The Ebolavirus genus contains several of the deadliest zoonotic viruses known. One of these, Bundibugyo virus (BDBV), has been the causative agent of two outbreaks of human disease that have resulted in 211 known cases with a case fatality rate of 33.6%.
Charles E. Lewis+8 more
wiley +1 more source
A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross [PDF]
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a complex neuropsychiatric disorder with a substantial genetic component. The Spontaneously Hypertensive Rats (SHR), considered as a good animal model of ADHD, also show less anxiety-like ...
Mormède, Pierre+5 more
core +3 more sources
Preformed lymphocytotoxic antibodies: The effects of class, titer and specificity on liver vs. heart allografts [PDF]
The effect on liver and heart allograft survival (ACI rats to Lewis rats) was studied after three methods of recipient presensitization and after different intervals between sensitization and transplantation.
Demetris, AJ+6 more
core +1 more source
Divergent risky decision-making and impulsivity behaviors in Lewis rat substrains with low genetic difference. [PDF]
Gabriel DBK+10 more
europepmc +1 more source
Unique Regulatory Properties of Mesangial Cells Are Genetically Determined in the Rat
Mesangial cells are glomerular cells of stromal origin. During immune complex mediated crescentic glomerulonephritis (Crgn), infiltrating and proliferating pro-inflammatory macrophages lead to crescent formation.
Behmoaras, J+7 more
core +3 more sources
Experimental diabetic animal models to study diabetes and diabetic complications. [PDF]
Athmuri DN, Shiekh PA.
europepmc +1 more source