Results 11 to 20 of about 4,642 (140)

Animal models of hypertension and concurrent organs injury. [PDF]

open access: yesAnimal Model Exp Med
Although hypertension is a frequently seen chronic condition across the world, its exact cause remains unclear. Animal models are beneficial for clarifying the pathogenic mechanism of hypertension and examining new treatments. An optimal animal model for studies on hypertension must well mimic human‐like hemodynamics and pathophysiological structural ...
Wang Y, Jiang X, Yang Z.
europepmc   +2 more sources

Features of the planimetric organization of the endocrine part of the pancreas in hypertensive rats of the SHR line

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
Analysis of the endocrine structure of the pancreas and assessment of its degree of heterogeneity is key to assessing such important physiological parameters as islet endocrinocyte mass in healthy people or functional reserve of β-cells in patients with
T. V. Ivanenko
doaj   +1 more source

Shaping the development of complex social behavior

open access: yesAnnals of the New York Academy of Sciences, Volume 1530, Issue 1, Page 46-63, December 2023., 2023
Abstract Early life experiences can have an enduring impact on the brain and behavior, with implications for stress reactivity, cognition, and social behavior. In particular, the neural systems that contribute to the expression of social behavior are altered by early life social environments.
James P. Curley, Frances A. Champagne
wiley   +1 more source

A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross

open access: yesBehavioral and Brain Functions, 2006
Background Attention deficit hyperactivity disorder (ADHD) is a complex neuropsychiatric disorder with a substantial genetic component. The Spontaneously Hypertensive Rats (SHR), considered as a good animal model of ADHD, also show less anxiety-like ...
Ramos André   +5 more
doaj   +1 more source

Contribution of animal models to diabetes research: Its history, significance, and translation to humans

open access: yesJournal of Diabetes Investigation, Volume 14, Issue 9, Page 1015-1037, September 2023., 2023
Animal models of diabetes and application to human studies ABSTRACT Diabetes mellitus is still expanding globally and is epidemic in developing countries. The combat of this plague has caused enormous economic and social burdens related to a lowered quality of life in people with diabetes.
Soroku Yagihashi
wiley   +1 more source

Changes in renal WT-1 expression preceding hypertension development [PDF]

open access: yes, 2016
Background: Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information.
Abud, María Angélica   +8 more
core   +2 more sources

Chemical Characterisation and Antihypertensive Effects of Locular Gel and Serum of Lycopersicum esculentum L. var. “Camone” Tomato in Spontaneously Hypertensive Rats

open access: yesMolecules, 2020
Blood pressure control in hypertensive subjects calls for changes in lifestyle, especially diet. Tomato is widely consumed and rich in healthy components (i.e., carotenoids, vitamins and polyphenols).
Paola Marcolongo   +12 more
doaj   +1 more source

Blood pressure and indices of glomerular filtration area in hypertensive and normotensive Prague rats [PDF]

open access: yes, 2000
The involvement of the kidney in the pathogenesis of hypertension has long been recognised, although the specific renal mechanisms underlying this phenomenon are still unknown.
Davis, J. M., Hellmann, H., Thurau, K.
core   +1 more source

Can Wistar rats be used as the normotensive controls for nerve morphometry investigations in spontaneously hypertensive rats (SHR)? Ratos Wistar podem ser utilizados como os controles normotensos dos ratos espontaneamente hipertensos (SHR) em investigações morfométricas de nervos periféricos?

open access: yesActa Cirúrgica Brasileira, 2011
PURPOSE: We compared the sural nerve morphology among Wistar (WR), Wistar-Kyoto (WKY) and Spontaneously hypertensive (SHR) rats, including the nerve fascicles and myelinated fibers morphometry.
Luciana Sayuri Sanada   +4 more
doaj   +1 more source

Blockade of alpha 2-adrenergic receptors in prelimbic cortex: impact on cocaine self-administration in adult spontaneously hypertensive rats following adolescent atomoxetine treatment [PDF]

open access: yes, 2017
RATIONALE: Research with the spontaneously hypertensive rat (SHR) model of attention deficit/hyperactivity disorder demonstrated that chronic methylphenidate treatment during adolescence increased cocaine self-administration established during adulthood ...
Baskin, Britahny M.   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy