Results 41 to 50 of about 4,642 (140)
Disease Models & Mechanisms, 2017 We previously mapped hypertension-related insulin resistance quantitative trait loci (QTLs) to rat chromosomes 4, 12 and 16 using adipocytes from F2 crosses between spontaneously hypertensive (SHR) and Wistar Kyoto (WKY) rats, and subsequently identified
Philip M. Coan +9 more
doaj +1 more source
Journal of Cellular and Molecular Medicine, Volume 29, Issue 23, December 2025.ABSTRACT Endoplasmic reticulum stress (ERS) emerges as a critical pathophysiological nexus in hypertension and related cardiovascular diseases. Chronic ERS activation via the IRE1α‐XBP1, ATF6, and PERK pathways drives vascular endothelial dysfunction (reduced NO bioavailability, increased ET‐1), renin‐angiotensin system (RAS) hyperactivation ...
Xin Ma +6 more
wiley +1 more source
Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions [PDF]
, 2010 Dexamethasone (DEX) is known to induce diabetes and dyslipidemia. We have compared fasting triacylglycerol and cholesterol concentrations across 20 lipoprotein fractions and glucose tolerance in control (standard diet) and DEX-treated 7-month-old males ...
Michaela Krupková +5 more
core +1 more source
Chemistry &Biodiversity, Volume 22, Issue 9, September 2025.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Von Willebrand Factor Gene Variants Associate with Herpes simplex Encephalitis.
PLoS ONE, 2016 Herpes simplex encephalitis (HSE) is a rare complication of Herpes simplex virus type-1 infection. It results in severe parenchymal damage in the brain.
Nada Abdelmagid +20 more
doaj +1 more source
Small RNA expression and strain specificity in the rat [PDF]
, 2010 Background Digital gene expression (DGE) profiling has become an established tool to study RNA expression. Here, we provide an in-depth analysis of small RNA DGE profiles from two different rat strains (BN-Lx and SHR) from six different rat tissues ...
Sam EV Linsen +3 more
core +1 more source
Role of the dopamine system in motor skill learning : implications for neurodevelopmental disorders [PDF]
, 2014 Dopamine (DA), released by midbrain neurons, is critical for motor performance, motor skill learning, and corticostriatal synaptic plasticity. Dysregulation of DAergic signaling in corticostriatal circuitry has also been implicated in several highly ...
Qian, Yu
core +1 more source
Effects of physical training and potassium supplementation on blood pressure, glucose metabolism and albuminuria of spontaneously hypertensive rats [PDF]
, 2014 Introduction: It is still controversial whether there are synergistic effects among different non-pharmacological interventions used in the treatment of hypertension.
Cesaretti, Mário Luís Ribeiro +5 more
core +2 more sources
, 2023 Clinical and Translational Science, Volume 16, Issue 12, Page 2413-2416, December 2023.
wiley +1 more source