Results 1 to 10 of about 129,705 (270)

Reagin synthesis in inbred strains of rats.

Journal of Allergy and Clinical Immunology, 1973
Reaginic antibody synthesis after intraperitoneal immunization with ovalbumin in aluminium hydroxide gel (Al(OH)3) has been evaluated in BN, F344 and ACI inbred strains of rats and compared to that in outbred Wistar rats. Regardless of the dose of antigen employed (0.1 mg, 0.01 mg, 0.001 mg), BN inbred and Wistar outbred rats produced comparable ...
S. Murphey, S. Brown, N. Miklós, P. Fireman   +3 more
semanticscholar   +4 more sources

Identification of the genetic background of laboratory rats through amplicon-based next-generation sequencing for single-nucleotide polymorphism genotyping. [PDF]

BMC Genom Data
Background Laboratory rats, as model animals, have been extensively used in the fields of life science and medicine. It is crucial to routinely monitor the genetic background of laboratory rats. The conventional approach relies on gel electrophoresis and
Lu M, Li K, Zhou Y, Xiao J.
europepmc   +2 more sources

Cholesterol Response in Inbred Strains of Rats, Rattus norvegicus [PDF]

The Journal of Nutrition, 1981
A hypercholesterolemic diet fed to rats revealed significant interstrain differences in plasma cholesterol levels. Hyperresponding and hyporesponding strains could be distinguished from normoresponding strains within 3 weeks. The increase in plasma cholesterol level was more than 300 mg/100 ml in the hyperresponding strains BN/Cpb, SD/Cpb and WE/Z and ...
L. V. Zutphen, M. Bieman
semanticscholar   +3 more sources

Phenotypic Variation in Strength Among Eleven Inbred Strains of Rats

Experimental Biology and Medicine, 1998
As a first step toward the long-range goal of identifying the genes that determine strength, we subjected 11 inbred strains of rats to three tests of muscular strength. The tests consisted of measuring (1) the force exerted by the rat as it was pulled by the base of the tail off a grid on the pan of a top-loading electronic balance (scale test); (2 ...
B. Biesiadecki, P. H. Brand, P. J. Metting, L. Koch, S. Britton   +4 more
semanticscholar   +4 more sources

Stardardized nomenclature for inbred strains of rats.

Transplantation, 1973
M. Festing, J. Staats
semanticscholar   +4 more sources

Establishing a Genetic Detection Protocol of Single Nucleotide Polymorphisms Panels in Inbred Rats Based on Multiplex PCR-LDR

Shiyan dongwu yu bijiao yixue, 2023
Objective To establish a set of single nucleotide polymorphisms (SNP) detection protocol for inbred rats based on multiplex PCR-ligase detection reaction (LDR).Methods A total of 40 rats SNP sites were selected on chromosomes 1-20 and X of rats among 5 ...
ZHAO Liya, NI Liju, ZHANG Caiqin, TANG Jianping, YAO Yangzheng, NIE Yanyan, GU Xiaoxue, ZHAO Ying   +7 more
doaj   +1 more source

A low coefficient of variation in hepatic triglyceride concentration in an inbred rat strain

Lipids in Health and Disease, 2020
Background Inbred strains are characterized by less genetic variation, which suggests usefulness of inbred strains for evaluations of various parameters.
Tomoko Shimoda, Shota Hori, Kenta Maegawa, Akari Takeuchi, Yeonmi Lee, Ga-Hyun Joe, Yasutake Tanaka, Hidehisa Shimizu, Satoshi Ishizuka   +8 more
doaj   +1 more source

Simulated childbirth injuries in an inbred rat strain [PDF]

Neurourology and Urodynamics, 2008
AbstractAimsVaginal distension (VD) in outbred rats has been shown to decrease urethral resistance, as well as increase the expression of the stem cell‐homing chemokine, monocyte chemotactic factor 3 (MCP‐3), but not stromal derived factor 1 (SDF‐1). The aim of this study was to determine if similar responses are induced by VD in an inbred rat strain ...
Hui Q. Pan, Margot S. Damaser, Mei Kuang, Lynn L. Woo, Adonis Hijaz, Raymond R. Rackley   +5 more
openaire   +3 more sources

Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages. [PDF]

PLoS ONE, 2012
Anthrax lethal factor (LF) is the protease component of anthrax lethal toxin (LT). LT induces pyroptosis in macrophages of certain inbred mouse and rat strains, while macrophages from other inbred strains are resistant to the toxin.
Kristina A Hellmich, Jonathan L Levinsohn, Rasem Fattah, Zachary L Newman, Nolan Maier, Inka Sastalla, Shihui Liu, Stephen H Leppla, Mahtab Moayeri   +8 more
doaj   +1 more source

Strain differences in delay discounting using inbred rats [PDF]

Genes, Brain and Behavior, 2009
A heightened aversion to delayed rewards is associated with substance abuse and numerous other neuropsychiatric disorders. Many of these disorders are heritable, raising the possibility that delay aversion may also have a significant genetic or heritable component.
Clare J. Wilhelm, Suzanne H. Mitchell
openaire   +3 more sources