Results 91 to 100 of about 97,044 (222)

Mitochondrial haplotype and sex modulate responses to endurance exercise training

The Journal of Physiology, EarlyView.
Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn, Tianhao Wei, Ryan Pettit‐Mee, Eunyoung Kim, Robert V. Musci, Jonathan Wanagat, Hoang Van M. Nguyen, Arlan Richardson, Hyunyoung Kim   +8 more
wiley   +1 more source

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

BMC Medical Genomics, 2009
Background MicroRNAs (miRNAs) are non-coding RNA molecules involved in post-transcriptional control of gene expression of a wide number of genes, including those involved in glucose homeostasis.
Fernandez Christina, Camps Carme, Barrett Amy, Kaisaki Pamela J, Wills Quin F, Taylor Jennifer M, Lockstone Helen E, Herrera Blanca M, Ragoussis Jiannis, Gauguier Dominique, McCarthy Mark I, Lindgren Cecilia M   +11 more
doaj   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Prediction of symbiotic nitrogen fixation in common bean (Phaseolus vulgaris L.) using unmanned aerial system remote sensing

The Plant Phenome Journal, Volume 8, Issue 1, December 2025.
Abstract Common bean (Phaseolus vulgaris L.) can fix atmospheric nitrogen (N) through symbiosis with Rhizobia species. This trait is often underutilized by growers and overlooked by breeders due to the laborious and costly evaluation techniques involved.
Madison Whyte, Mason Jackson, Leonardo Volpato, Evan M. Wright, Valerio Hoyos‐Villegas, Francisco E. Gomez   +5 more
wiley   +1 more source

Repurposing the Antidepressant Sertraline: A Systematic Scoping Review of Its Anticancer Mechanisms

Pharmacology Research &Perspectives, Volume 13, Issue 5, October 2025.
A multi‐targeted antidepressant with strong preclinical anticancer activity, sertraline represents a candidate for therapeutic repurposing. ABSTRACT Drug repurposing offers a cost‐effective and time‐efficient strategy for identifying new cancer therapies. Sertraline, a widely prescribed selective serotonin reuptake inhibitor (SSRI), has shown promising
Ciara B. Blum, McCarlie‐Jayne Dohrmann, Lucia McCarthy, Milli McMenamin, Liam A. O'Callaghan   +4 more
wiley   +1 more source

Microbial diversity and function in the rhizosphere microbiome: Driving forces and monitoring approaches

Agrosystems, Geosciences &Environment, Volume 8, Issue 3, September 2025.
Abstract As an ecological unit, the rhizosphere microbiome preserves an enormous and largely unexplored diversity of microbes that play essential roles in plant health and soil functions. Omics technologies encompassing high‐throughput approaches such as metagenomics, metatranscriptomics, and metaproteomics provide helpful tools to unravel the ...
Chinenyenwa Fortune Chukwuneme, Olubukola Oluranti Babalola   +1 more
wiley   +1 more source

Neem (Azadirachta indica): A Miracle Herb; Panacea for All Ailments

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
This comprehensive review highlights the diverse phytochemicals derived from neem leaves, extraction techniques, and their medicinal value in the treatment of multiple medical conditions. This miraculous plant has significant potential for enhanced effectiveness.
Tabussam Tufail, Huma Bader Ul Ain, Aiman Ijaz, Muhammad Adnan Nasir, Ali Ikram, Sana Noreen, Muhammad Tayyab Arshad, Muhammed Adem Abdullahi   +7 more
wiley   +1 more source

Identification and mapping of quantitative trait loci for Fusarium head blight resistance in a synthetic hexaploid × hard red spring wheat population

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Fusarium head blight (FHB), caused by Fusarium graminearum Schwabe, is one of the most devastating diseases in wheat (Triticum aestivum L.). The synthetic hexaploid wheat line Largo was developed from a cross between the durum wheat [T. turgidum ssp. durum (Desf.) Husn.] variety Langdon and the Aegilops tauschii Cosson accession PI 268210, and
Agnes Szabo‐Hever, Jyoti S. Sharma, Justin D. Faris, Shaobin Zhong, Timothy L. Friesen, Jason D. Fiedler, Andrew J. Green, Guihua Bai, Elias M. Elias, Steven S. Xu   +9 more
wiley   +1 more source

Behavioural features of alcohol-preferring rats: focus on inbred strains.

Alcohol and Alcoholism, 1999
D. Overstreet, A. Rezvani, A. Parsian
semanticscholar   +1 more source

Genetic mapping of Ascochyta blight resistance in an ILL6002 × Indianhead lentil mapping population

The Plant Genome, Volume 18, Issue 3, September 2025.
Abstract Ascochyta blight of lentil (Lens culinaris Medik.) is a fungal disease caused by Ascochyta lentis. This study was carried out to identify the location of quantitative trait loci (QTL) associated with resistance from the accession Indianhead, and how these vary between the recently identified pathotypes of A. lentis.
Em L. Thackwray, Bernadette M. Henares, Christina R. Grime, Bethany L. Clark, Robert C. Lee, Lars G. Kamphuis   +5 more
wiley   +1 more source