Results 11 to 20 of about 49,631 (197)

Strain differences in delay discounting using inbred rats [PDF]

open access: yesGenes, Brain and Behavior, 2009
A heightened aversion to delayed rewards is associated with substance abuse and numerous other neuropsychiatric disorders. Many of these disorders are heritable, raising the possibility that delay aversion may also have a significant genetic or heritable component.
C J, Wilhelm, S H, Mitchell
openaire   +2 more sources

Simulated childbirth injuries in an inbred rat strain [PDF]

open access: yesNeurourology and Urodynamics, 2008
AbstractAimsVaginal distension (VD) in outbred rats has been shown to decrease urethral resistance, as well as increase the expression of the stem cell‐homing chemokine, monocyte chemotactic factor 3 (MCP‐3), but not stromal derived factor 1 (SDF‐1). The aim of this study was to determine if similar responses are induced by VD in an inbred rat strain ...
Lynn L, Woo   +5 more
openaire   +2 more sources

Shear Stress Is Differentially Regulated Among Inbred Rat Strains [PDF]

open access: yesCirculation Research, 2003
An important compensatory response to atherosclerosis is vascular remodeling, with maintenance of vessel lumen diameter and shear stress. Both hemodynamic and environmental factors contribute to vascular remodeling and shear stress regulation, and the process is probably also influenced by genetic factors.
Jamila, Ibrahim   +2 more
openaire   +2 more sources

Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1.

open access: yesPLoS Pathogens, 2010
Anthrax lethal toxin (LT) is a bipartite protease-containing toxin and a key virulence determinant of Bacillus anthracis. In mice, LT causes the rapid lysis of macrophages isolated from certain inbred strains, but the correlation between murine ...
Zachary L Newman   +8 more
doaj   +1 more source

Innate Resistance to Leishmania amazonensis Infection in Rat Is Dependent on NOS2

open access: yesFrontiers in Microbiology, 2021
Leishmania infection causes diverse clinical manifestations in humans. The disease outcome is complicated by the combination of many host and parasite factors.
Yun-Fu Chen   +11 more
doaj   +1 more source

Quantification of DNA Damage in Different Tissues in Rats with Heart Failure [PDF]

open access: yesArquivos Brasileiros de Cardiologia
Background: Chronic heart failure (CHF) is a complex syndrome which comprises structural and functional alterations in the heart in maintaining the adequate blood demand to all tissues.
Giuseppe Potrick Stefani   +6 more
doaj   +3 more sources

Recurrent Regional Allelic Imbalance in Chromosome 15 in Rat Endometrial Adenocarcinomas [PDF]

open access: yesCell Journal, 2010
Objective: Animals of the inbred BDII rat strain are genetically predisposed to endometrialadenocarcinomas (EAC) and can be used to model human cancer.
Ahmad Hamta, Farah Talebbeigy
doaj  

Strain differences in seizure-induced cell death following pilocarpine-induced status epilepticus

open access: yesNeurobiology of Disease, 2012
Mouse strains differ from one another in their susceptibility to seizure-induced excitotoxic cell death. Previously, we have demonstrated that mature inbred strains of mice show remarkable genetic differences in susceptibility to the neuropathological ...
P. Elyse Schauwecker
doaj   +1 more source

Influence of Age and Genetic Background on Ethanol Intake and Behavioral Response Following Ethanol Consumption and During Abstinence in a Model of Alcohol Abuse

open access: yesFrontiers in Behavioral Neuroscience, 2022
Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction ...
Silvia Corongiu   +7 more
doaj   +1 more source

Worm burdens in outbred and inbred laboratory rats with morphometric data on Syphacia muris (Yamaguti, 1935) Yamaguti, 1941 (Nematoda, Oxyuroidea)

open access: yesMemorias do Instituto Oswaldo Cruz, 2001
Syphacia muris worm burdens were evaluated in the rat Rattus norvegicus of the strains Wistar (outbred), Low/M and AM/2/Torr (inbred), maintained conventionally in institutional animal houses in Brazil. Morphometrics and illustration data for S.
Roberto Magalhães Pinto   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy