Results 11 to 20 of about 97,044 (222)

Phenotypic Variation in Strength Among Eleven Inbred Strains of Rats

Experimental Biology and Medicine, 1998
As a first step toward the long-range goal of identifying the genes that determine strength, we subjected 11 inbred strains of rats to three tests of muscular strength. The tests consisted of measuring (1) the force exerted by the rat as it was pulled by the base of the tail off a grid on the pan of a top-loading electronic balance (scale test); (2 ...
Lauren G. Koch, Paul H. Brand, Steven L. Britton, Brandon J. Biesiadecki, P. J. Metting   +4 more
openaire   +4 more sources

FURTHER STUDIES OF THE STIMULATION OF DNA SYNTHESIS IN CULTURES OF SPLEEN CELL SUSPENSIONS BY HOMOLOGOUS CELLS IN INBRED STRAINS OF MICE AND RATS

Journal of Experimental Medicine, 1965
The early proliferative response previously demonstrated in rabbits has now been shown to follow the mixing of spleen cell suspensions from 2 inbred strains of mice or rats.
R. Dutton
semanticscholar   +1 more source

Phenotypic and gene expression differences between DA, BN and WOKW rats. [PDF]

PLoS ONE, 2012
BACKGROUND: Because inbred rat strains are widely used as laboratory models, knowledge of phenotypic and genetic variations between strains will be useful to obtain insight into the relationship between different strains.
Jörn Lange, Thomas Barz, Axel Ekkernkamp, Barbara Wilke, Ingrid Klöting, Niels Follak   +5 more
doaj   +1 more source

Genetic factors control nicotine self-administration in isogenic adolescent rat strains. [PDF]

PLoS ONE, 2012
Adult cigarette smokers usually become dependent on cigarettes during adolescence. Despite recent advances in addiction genetics, little data delineates the genetic factors that account for the vulnerability of humans to smoke tobacco.
Hao Chen, Katie A Hiler, Elizabeth A Tolley, Shannon G Matta, Burt M Sharp   +4 more
doaj   +1 more source

Innate Resistance to Leishmania amazonensis Infection in Rat Is Dependent on NOS2

Frontiers in Microbiology, 2021
Leishmania infection causes diverse clinical manifestations in humans. The disease outcome is complicated by the combination of many host and parasite factors.
Yun-Fu Chen, Si-Fei Yu, Chang-You Wu, Na Wu, Jia Shen, Juan Shen, Jiang-Mei Gao, Yan-Zi Wen, Geoff Hide, De-Hua Lai, Zhao-Rong Lun, Zhao-Rong Lun   +11 more
doaj   +1 more source

Quantification of DNA Damage in Different Tissues in Rats with Heart Failure [PDF]

Arquivos Brasileiros de Cardiologia
Background: Chronic heart failure (CHF) is a complex syndrome which comprises structural and functional alterations in the heart in maintaining the adequate blood demand to all tissues.
Giuseppe Potrick Stefani, Ramiro Barcos Nunes, Douglas Dalcin Rossato, Vitor Scotta Hentschke, Marlise Di Domenico, Pedro Dal Lago, Cláudia Ramos Rhoden   +6 more
doaj   +3 more sources

Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1.

PLoS Pathogens, 2010
Anthrax lethal toxin (LT) is a bipartite protease-containing toxin and a key virulence determinant of Bacillus anthracis. In mice, LT causes the rapid lysis of macrophages isolated from certain inbred strains, but the correlation between murine ...
Zachary L Newman, Morton P Printz, Shihui Liu, Devorah Crown, Laura Breen, Sharmina Miller-Randolph, Pamela Flodman, Stephen H Leppla, Mahtab Moayeri   +8 more
doaj   +1 more source

Recurrent Regional Allelic Imbalance in Chromosome 15 in Rat Endometrial Adenocarcinomas [PDF]

Cell Journal, 2010
Objective: Animals of the inbred BDII rat strain are genetically predisposed to endometrialadenocarcinomas (EAC) and can be used to model human cancer.
Ahmad Hamta, Farah Talebbeigy
doaj  

Influence of Age and Genetic Background on Ethanol Intake and Behavioral Response Following Ethanol Consumption and During Abstinence in a Model of Alcohol Abuse

Frontiers in Behavioral Neuroscience, 2022
Genetic background and age at first exposure have been identified as critical variables that contribute to individual vulnerability to drug addiction. Evidence shows that genetic factors may account for 40–70% of the variance in liability to addiction ...
Silvia Corongiu, Christian Dessì, Elena Espa, Augusta Pisanu, Annalisa Pinna, Daniele Lecca, Sandro Fenu, Cristina Cadoni   +7 more
doaj   +1 more source

Strain differences in seizure-induced cell death following pilocarpine-induced status epilepticus

Neurobiology of Disease, 2012
Mouse strains differ from one another in their susceptibility to seizure-induced excitotoxic cell death. Previously, we have demonstrated that mature inbred strains of mice show remarkable genetic differences in susceptibility to the neuropathological ...
P. Elyse Schauwecker
doaj   +1 more source