Results 11 to 20 of about 23,411 (167)
Frontiers in Psychiatry, 2020 Individual differences or vulnerabilities must exist which bias some individuals toward psychopathology while others remain resilient in the face of trauma.
Daniel Paul Miller +5 more
doaj +1 more source
Shaping the development of complex social behavior
Annals of the New York Academy of Sciences, Volume 1530, Issue 1, Page 46-63, December 2023., 2023 Abstract Early life experiences can have an enduring impact on the brain and behavior, with implications for stress reactivity, cognition, and social behavior. In particular, the neural systems that contribute to the expression of social behavior are altered by early life social environments.
James P. Curley, Frances A. Champagne
wiley +1 more source
Animal Models and Experimental Medicine, Volume 6, Issue 5, Page 452-463, October 2023., 2023 The construction of the most representative AAV animal models that are used as powerful tools for investigating disease pathogenesis and testing pre‐clinical therapeutics. (A) The representative active MPO‐AAV model, Enhanced EAV rat model by NTS trigger. (B) The representative passive MPO‐AAV model, Anti MPO ANCA transfer model. (C) The representative
Fei Huang +4 more
wiley +1 more source
The Journal of Pathology, Volume 257, Issue 3, Page 300-313, July 2022., 2022 Abstract P2RX7, an ionotropic receptor for extracellular adenosine triphosphate (ATP), is expressed on immune cells, including macrophages, monocytes, and dendritic cells and is upregulated on nonimmune cells following injury. P2RX7 plays a role in many biological processes, including production of proinflammatory cytokines such as interleukin (IL)‐1β ...
Maria Prendecki +11 more
wiley +1 more source
Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes
European Journal of Immunology, Volume 52, Issue 5, Page 717-729, May 2022., 2022 Rat ILCs are here defined and characterized across multiple tissues, and we have defined the borders between rat NK cells and ILC1s via scRNA‐Seq. Variations of intestinal ILC frequencies in individual rats were mapped against composition of the commensal microbiota. Abstract Innate lymphoid cells (ILCs) are important for tissue immune homeostasis, and
Amanda Sudworth +7 more
wiley +1 more source
Impact of the Aversive Effects of Drugs on Their Use and Abuse
Behavioural Neurology, Volume 2022, Issue 1, 2022., 2022 Drug use and abuse are complex issues in that the basis of each may involve different determinants and consequences, and the transition from one to the other may be equally multifaceted. A recent model of the addiction cycle (as proposed by Koob and his colleagues) illustrates how drug‐taking patterns transition from impulsive (acute use) to compulsive
Anthony L. Riley +3 more
wiley +1 more source
Bone healing of mandibular critical-size defects in spontaneously hypertensive rats
Brazilian Oral Research, 2013 Few articles have shown changes in bone metabolism caused by hypertension. The objective of this study was to investigate the relationship between hypertension and bone healing.
Veronica Kei Len Chin +2 more
doaj +1 more source
Genes, Brain and Behavior, Volume 20, Issue 8, November 2021., 2021 Seven inbred strains of rats show different dose‐dependent escalation of operant responses for oral oxycodone. Abstract The steady rise in prescription opioids such as oxycodone has led to a virulent epidemic of widespread abuse and deaths in the United States; approximately 80% of affected individuals initiate the habitual use of oxycodone by using ...
Burt M. Sharp +4 more
wiley +1 more source
Unique Regulatory Properties of Mesangial Cells Are Genetically Determined in the Rat [PDF]
, 2014 Mesangial cells are glomerular cells of stromal origin. During immune complex mediated crescentic glomerulonephritis (Crgn), infiltrating and proliferating pro-inflammatory macrophages lead to crescent formation.
Behmoaras, J +7 more
core +10 more sources
Avoidance Expression in Rats as a Function of Signal-Shock Interval: Strain and Sex Differences
Frontiers in Behavioral Neuroscience, 2015 Inbred Wistar Kyoto (WKY) rats express inhibited temperament, increased sensitivity to stress, and exaggerated expressions of avoidance. A long-standing observation for lever press escape/avoidance learning in rats is the duration of the warning signal (
Richard J Servatius +14 more
doaj +1 more source