Results 191 to 200 of about 322,728 (311)

Depression and Gastrointestinal Health Abnormalities: Treatment Approaches from the Perspective of Traditional Chinese Medicine. [PDF]

Neuropsychiatr Dis Treat
Lu K, Tang A, Liu Y, Li L, Fang R, Zhang S, Chen Y, Cao F.   +7 more
europepmc   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Light-aversion and cephalic allodynia in an intravenous CGRP model of migraine-like behaviour in male and female rats. [PDF]

J Headache Pain
Andersen VK, Hansen BS, Fungbrant E, Hestehave S, Haanes KA, Nordahl KML.   +5 more
europepmc   +1 more source

Polyphenol‐Based Biomaterials Against Cancer Radio/Chemotherapy‐Induced Intestinal Toxicity

Advanced NanoBiomed Research, EarlyView.
Radiotherapy/chemotherapy often causes intestinal toxicity, impairing cancer patients’ quality of life and treatment efficacy. Polyphenols protect against this injury via multiple mechanisms, but face oral use limitations. This review outlines their protective mechanisms and delivery challenges, highlighting recent oral delivery advances and future ...
Jixu Lu, Jing Chen, Ji Zhu, Lixin Ru, Dongxiao Zhang   +4 more
wiley   +1 more source

In Vivo Prostate Cancer Modelling: From the Pre-Clinical to the Clinical Setting. [PDF]

Life (Basel)
Nascimento-Gonçalves E, Azevedo T, Medeiros C, Faustino-Rocha AI.   +3 more
europepmc   +1 more source

On the Molecular Diffusion Dynamics Between Subcutaneous Tissue and Microneedles for Wearable Continuous Glucose Monitoring

Advanced NanoBiomed Research, EarlyView.
In this study, we investigate the dynamics of glucose diffusion between subcutaneous tissue and hydrogel‐filled microneedles. Specifically, we examine how hydrogel thickness, microneedle size, and glucose concentration influence diffusion. This study provides an experimental reference to the wearable biosensor community researching microneedle‐based ...
Wensheng Lin, Binbin Cui, Xuecheng He, Suo Tu, Shilei Dai, Xinran Zhang, Ivo Pang, Xiaonan Chen, Jixiang Zhu, Shiming Zhang   +9 more
wiley   +1 more source

Can Environmental Enrichment Mitigate Cell Apoptosis in the Central Nervous System Under Adverse Health Conditions? A Systematic Review. [PDF]

Clin Transl Sci
de Sousa Fernandes MS, Ferreira DJS, Yagin FH, Badicu G, Santos GCJ, Guedes MCS, Souto FO, Ardigò LP.   +7 more
europepmc   +1 more source

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

Nutritional and Phytochemical Compositions of <i>Peperomia pellucida</i> (L). Kunth from Bogor, West Java, Indonesia, and Its Hypoglycemic Effects in Normoglycemic Sprague-Dawley Rats Subjected to an Acute Glucose Load. [PDF]

J Exp Pharmacol
Teodhora, Hendriani R, Sumiwi SA, Levita J.   +3 more
europepmc   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source