Results 91 to 100 of about 342,681 (291)

COMPARISON OF THE COMPLETE NUCLEOTIDE SEQUENCES OF MITOCHONDRIAL DNA FROM WISTAR AND OXYS RAT STRAINS MAINTAINED AT THE INSTITUTE OF CYTOLOGY AND GENETICS SB RAS

open access: yesВавиловский журнал генетики и селекции, 2015
The study was performed with complete nucleotide sequences of the mitochondrial DNA of Wistar rats and prematurely aging OXYS rats, sensitive to the cataractogenic effect of galactose, kept at the Gene pool of laboratory animals shared access center ...
R. A. Maksyutov   +7 more
doaj  

Discriminating Different Classes of Toxicants by Transcript Profiling [PDF]

open access: yes, 2004
Male rats were treated with various model compounds or the appropriate vehicle controls. Most substances were either well-known hepatotoxicants or showed hepatotoxicity during preclinical testing.
Albertini, Silvio   +6 more
core   +2 more sources

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Granulocyte-colony stimulating factor in experimental stroke and its effects on infarct size and functional outcome: a systematic review [PDF]

open access: yes, 2009
Background Granulocyte-colony stimulating factor (G-CSF) shows promise as a treatment for stroke. This systematic review assesses G-CSF in experimental ischaemic stroke.
Alvarez-Dolado   +55 more
core   +2 more sources

Highly Efficient Classification of Time‐Series Based on Resistive Switching Cluster‐Assembled Materials

open access: yesAdvanced Intelligent Systems, EarlyView.
Cluster‐assembled nanocomposite devices are employed for the classification of neuronal traces, without any preprocessing of the input time‐series or prior training of the nonlinear devices. The classification method relies on the statistical analysis of the device's output time‐series, achieving higher classification accuracy compared to more energy ...
Filippo Profumo   +5 more
wiley   +1 more source

Innovative insights into the effects of a high‐sucrose diet on pancreatic health and the therapeutic role of empagliflozin in type 2 diabetes: An experimental study

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Histologic assessment of pancreatic tissues using the H&E method (Scale bar = 100 μm. Images were captured at 400×). A high‐sucrose diet induced structural damage in pancreatic tissue, whereas empagliflozin treatment markedly improved these histological alterations.
Emad Gholami   +7 more
wiley   +1 more source

Biochemical characterisation of a Kunitz-type inhibitor from Tamarindus indica L. seeds and its efficacy in reducing plasma leptin in an experimental model of obesity

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2018
A trypsin inhibitor isolated from tamarind seed (TTI) has satietogenic effects in animals, increasing the cholecystokinin (CCK) in eutrophy and reducing leptin in obesity. We purified TTI (pTTI), characterised, and observed its effect upon CCK and leptin
Amanda Fernandes de Medeiros   +10 more
doaj   +1 more source

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the developing male Wistar(Han) rat II: chronic dosing causes developmental delay [PDF]

open access: yes, 2007
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure continuous exposure of the fetus. 5-6 week old rats were exposed
Bell, David Robert   +11 more
core   +1 more source

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats [PDF]

open access: yes, 2014
Copyright @ 2013 The authors. This work is licensed under a Creative Commons Attribution 3.0 Unported License.Obesity is a risk factor for sepsis morbidity and mortality, whereas the hypothalamic-pituitary-adrenal (HPA) axis plays a protective role in ...
Ahima   +40 more
core   +1 more source

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