Results 151 to 160 of about 159,497 (267)

Epigenetic regulation of the transcriptional activity of genes mediating the neuroprotective activity of ceftriaxone in the brain in a rat model of sporadic Alzheimer disease: the involvement of histone deacetylase 1. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Bashirzade AA, Tikhonova MA, Belichenko VM, Fedoseeva LA, Belyaev MD, Renn TY, Chang HM, Kolosova NG, Belyaev ND, Amstislavskaya TG.   +9 more
europepmc   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source

Diet enriched in saturated fatty acids alters mean arterial blood pressure and fat metabolism but not autonomic balance in rats. [PDF]

Braz J Med Biol Res
Rodrigues THG, Arcoverde-Mello APFC, Simões-Alves AC, Silva GMD, Lima TRLA, Fernandes MP, Nogueira VO, Wanderley AG, Costa-Silva JH.   +8 more
europepmc   +1 more source

Diabetes‐Induced Testicular Injury: Potential Protective Roles of Curcumin, Garcinia kola, and Momordica charantia in Rats

Andrology, EarlyView.
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley   +1 more source

The Wistar-Kyoto rat as a model relevant to inattentive ADHD: substrain variability and affective comorbidity. [PDF]

Pharmacol Rep
Gaik N, Dzierkacz E, Faron-Górecka A.
europepmc   +1 more source

Role of ANO1‐Expressing PDGFRα+ Smooth Muscle Cells in Generating Spontaneous Phasic Contractions of the Rodent Epididymis

Andrology, EarlyView.
ABSTRACT Background Spontaneous phasic contractions (SPCs) in the epididymal duct play an important role in transport and maturation of sperm. In proximal cauda of the rat epididymis, platelet‐derived growth factor receptor α (PDGFRα)‐positive smooth muscle cells (SMCs) generate ANO1 Ca2+‐activated chloride channels (CaCCs)‐dependent spontaneous ...
Wataru Kudo, Hiromichi Takano, Toshiya Izuchi, Retsu Mitsui, Kyoko Miwa‐Nishimura, Hikaru Hashitani   +5 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

An exploratory 12-week pilot study of gut microbiota and body-weight patterns during sodium nitrite exposure and Lactobacillus plantarum 299v supplementation in Wistar rats. [PDF]

BMC Microbiol
Duman E, Keser A, Balcı TN, Çetiner Ö, Kavruk M, Dursun AD, Özalp VC.   +6 more
europepmc   +1 more source