Medicinal Research Reviews, EarlyView.ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller +5 more
wiley +1 more source
METTL3-Mediated m<sup>6</sup>A Regulation of GDF11 Promotes Socket Healing in Diabetic Rats. [PDF]
Diabetes Metab Syndr ObesGuo D, Zhang B.
europepmc +1 more source
Blood-brain barrier disruption and perivascular beta-amyloid accumulation in the brain of aged rats with spontaneous hypertension: Evaluation with dynamic contrast-enhanced magnetic resonance imaging [PDF]
, 2018 Chen, Wei +8 more
core +2 more sources
Exploring Autophagy Inducing Molecules: Targeting Diverse Pathways in Alzheimer's Disease Management
Medicinal Research Reviews, EarlyView.ABSTRACT Neurodegenerative disorders, including Alzheimer's disease (AD), impose a significant burden on society due to their progressive nature and the associated healthcare costs. Autophagy, a vital cellular degradation process, has emerged as a promising therapeutic target in these disorders.
Baljinder Singh +4 more
wiley +1 more source
Hypoglycemic and Hypolipidemic Effects of <i>Leonotis mollisima</i> Aqueous Leaf Extract in Type 2 Diabetic Rats. [PDF]
J Exp PharmacolStephen N +4 more
europepmc +1 more source
Molecular Nutrition &Food Research, EarlyView.Pollutant‐induced epithelial damage also leads to a cascade of harmful effects, including reduced mucus secretion, decreased luminal pH, and enhanced absorption of toxins. These changes contribute to oxidative stress (↑ malondialdehyde (MDA); ↓ superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), and heightened ...
Meysam Zarezadeh Ph.D. +5 more
wiley +1 more source
Comparative analysis of autonomic effects of ketamine-xylazine in normotensive and hypertensive rats. [PDF]
Braz J Med Biol ResSantos PS +14 more
europepmc +1 more source
Molecular Nutrition &Food Research, EarlyView.Celiac disease (CD) is triggered by gluten in genetically predisposed individuals and is mainly treated with a gluten‐free diet. However, symptoms may persist. This review explores how certain Bifidobacterium strains may reduce inflammation and gluten toxicity through six mechanisms, including modulation of immune responses and gut microbiota.
Taynara Cipriano Scherer +7 more
wiley +1 more source
Understanding the impact of streptozotocin on diabetic male infertility: perspectives from rodent models and pharmacological networking. [PDF]
BMC Pharmacol ToxicolAsghar MA +8 more
europepmc +1 more source
Molecular Nutrition &Food Research, EarlyView.This study compared the preventive effects of dietary resistant starch (RS2) from maize and d‐fagomine (FG) from buckwheat on cardiometabolic risk factors in high‐fat (HF) diet‐fed rats. Wistar‐Kyoto rats (n = 11–12/group) received STD, HF, HF + RS, or HF + FG diets for 10 weeks.
Bernat Miralles‐Pérez +10 more
wiley +1 more source