Results 191 to 200 of about 1,545,547 (221)

Subchronic Toxicity of Pentostatin in Wistar Rats

Toxicologic Pathology, 1994
Pentostatin, an adenosine deaminase inhibitor, has been approved for the treatment of refractory hairy cell leukemia. In a preclinical toxicity study, Wistar rats were administered 0, 1, 10. 25, and 50 mg/kg (0, 6, 60, 150, and 300 mg/m2, respectively) pentostatin intravenously once a week for 26 wk (1.5-75-fold above the therapeutic dose in humans ...
Cynthia L. Courtney, Kathleen L. Hawkins, Charles E. Rothwell   +2 more
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Developmental Toxicity of Homobrassinolide in Wistar Rats

International Journal of Toxicology, 2010
Brassinosteroids (BRs) are close analogues of animal cholesterol. Brassinosteroids have shown their great value as yield promoters of a variety of plants. In view of its steroidal moiety and recent use in agriculture in many countries, the teratogenic potential of homobrassinolide (HBR) was evaluated in Wistar rats.
Yogeshkumar V. Murkunde, P. Balakrishna Murthy   +1 more
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A revaluation of the haemoglobin electrophoretogram of the wistar rat

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1971
Abstract 1. 1. Haemoglobins of Wistar rats have been examined by starch and polyacrylamide gel electrophoresis 2. 2. Two haemoglobins are produced during yolk sac erythropoiesis, and two additional haemoglobins appear during liver erythropoiesis. 3. 3. All four haemoglobins persist in the adult. 4. 4.
Norman Maclean, Andrew R.E. Shaw
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Hematological Characteristics of the BB Wistar Rat

Veterinary Clinical Pathology, 1983
SummaryComplete blood counts, differential white blood cell and platelet counts were performed on male and female BB Wistar diabetic rats (BBWd), their nondiabetic siblings (BBWnd) and outbred Wistar rats of the line from which the BB Wistar rats were derived.
James R. Wright, David W. Covey, Allan J. Yates, John C. Neff, Pierre Thibert, Niranjan T. Shah   +5 more
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Cardioprotective Effect of Saffron Extract and Safranal in Isoproterenol-Induced Myocardial Infarction in Wistar Rats

Iranian Journal of Basic Medical Sciences, 2013
Objective(s): This study was designed to evaluate the cardioprotective effect of Crocus sativus L. (saffron) aqueous extract and safranal, the major constituent of the essential oil of saffron, on lipid peroxidation, biochemical parameters and ...
R. Mehdizadeh, M. Parizadeh, Alireza Khooei, S. Mehri, H. Hosseinzadeh   +4 more
semanticscholar   +1 more source

Teratogenic Effect of Semicarbazide in Wistar Rats

Neonatology, 1986
Five groups of pregnant Wistar rats were injected intraperitoneally with a single dose of semicarbazide (SC) on day 5, 7, 10, 13, or 15 of gestation. The lots in each group received either 50, 75, 100 or 150 mg/kg SC. A sixth group received 17 mg/kg of the drug during the entire course of pregnancy.
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Anticholinesterasic Activity of Endosulfan in Wistar Rats

Bulletin of Environmental Contamination and Toxicology, 2011
The in vivo and in vitro effects of the pesticide endosulfan on the cholinesterase (ChE) activity were investigated in rats. ChE activity decreased in dams and in male pups within 65 days corresponding to 35% and 32% of inhibition respectively in the higher endosulfan dose (1.5 mg/kg).
Paulo Roberto Dalsenter, Delia Carolina Olmedo, Kelly Cristina Soares, Lilian Nicaretta, Sandra Crestani, Maria Consuelo Andrade Marques, Helena Cristina Silva de Assis   +6 more
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Tumor-Induced Anorexia in the Wistar Rat

Science, 1981
The transplantable Leydig cell tumor of Wistar rats, LTW(m), caused decreased food consumption and weight loss in the host within 2 weeks of implantation. The tumor was small, did not metastasize, and did not affect several parameters of biochemical function.
John P. Mordes, Aldo A. Rossini
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Teratogenicity of ionic cadmium in the Wistar rat

Archives of Toxicology, 1987
In rats of the present (re-derived) Wistar-Porton strain that are dosed either intravenously (i.v.), or intraperitoneally (i.p.) with Cd (1.25 mg/kg body weight) on day 12 of gestation (gd 12), foetal uptake of Cd is at least 6-fold greater than that reported in an earlier study (Webb and Samarawickrama 1981).
D. Holt, M. Webb
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Toxicology Reference Data for the Wistar Rat

1982
Sixty-six observations on Wistar rats, including body and organ weights, biochemistry, hematology, and urinalysis have been compiled over a period of 16 years. A statistical analysis of these observations involved 3,400 Wistar rats that served as controls in toxicity studies.
P. J. Lewi, R. P. Marsboom
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