Results 131 to 140 of about 3,497,773 (355)

Sexual dimorphism in basal and post stress parameters of neuro-endocrine-immune complex, metabolome, electrocardiogram, and gastric mucosa at rats

open access: yesJournal of Education, Health and Sport
Introduction and aim. Previously, we found significant associations between sex index and a number of parameters of the neuro-endocrine-immune complex and metabolome.
Oksana Fihura   +10 more
doaj   +1 more source

Reduction of Reactive Oxygen Species Ameliorates Metabolism-Secretion Coupling in Islets of Diabetic GK Rats by Suppressing Lactate Overproduction [PDF]

open access: bronze, 2013
Mayumi Sasaki   +10 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

MORPHOLOGICAL FEATURES OF THE SUBMUCOSAL GLANDS OF THE RAT DUODENUM UNDER THE EFFECT OF THE COMPLEX OF FOOD ADDITIVES

open access: yesКлінічна та профілактична медицина
Aim. To establish the dynamics of changes in the morphometric parameters of the acini of the submucosal glands of the rat duodenum under normal conditions and under the complex effect of food additives. Materials and methods.
Kostiantyn V. Shevchenko   +6 more
doaj   +1 more source

MicroRNA‐130a regulates neurological deficit and angiogenesis in rats with ischaemic stroke by targeting XIAP [PDF]

open access: gold, 2020
Wenjing Deng   +6 more
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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