Results 111 to 120 of about 1,831,838 (319)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

EVIDENCE FOR FREE-RADICAL MEDIATED LIPID PEROXIDATION IN RATS AFTER COLD-IMMERSION STRESS

open access: yes, 2017
The role of cold immersion stress for the free-radical mediated lipid peroxidation in rat plasma and erythrocytes was studied. A model of cold-induced stress in rats was created.
Galunska, B.   +3 more
core   +1 more source

Pancreatitis in the Rat

open access: yesExperimental Biology and Medicine, 1965
Conclusions and summaryWe have demonstrated that ligation of the common bile duct in the rat is followed within a few days by necrotizing hemorrhagic pancreatitis, considerable edema of the gland, fat necrosis, and often relatively large amounts of yellow ascitic fluid.
openaire   +2 more sources

RATS AND PLAGUE. [PDF]

open access: yesThe Lancet, 1902
n ...
openaire   +2 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Intestinal Electric Stimulation Accelerates Whole Gut Transit and Promotes Fat Excrement in Conscious Rats

open access: yes, 2009
*_Introduction:_* Intestinal electric stimulation (IES) is proposed as a potential tool for the treatment of morbid obesity. Our previous study showed that IES with one pair of electrodes accelerated intestinal transit and decreased fat absorption in a ...
Ying Sun, Jiande Chen
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Classification of Epileptic Seizures by Simple Machine Learning Techniques: Application to Animals’ Electroencephalography Signals

open access: yesIEEE Access
Detection and prediction of the onset of seizures are among the most challenging problems in epilepsy diagnostics and treatment. Small electronic devices capable of doing that will improve the quality of life for epilepsy patients while also open new ...
Illia Pidvalnyi   +10 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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