Results 101 to 110 of about 2,005,912 (260)
The neuronal and synaptic representations of spatial release from masking in the rat auditory cortex
Frontiers in NeuroscienceIn complex acoustic environments, both humans and animals are frequently exposed to sounds from multiple sources. The detection threshold for a target sound (or probe) can be elevated by interference sounds (masker) originating from various locations ...
Guanhua Chen, Jiping Zhang
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The organisational effects of adolescent gonadal hormones on behavioural development in rats [PDF]
, 2015 Gonadal steroid hormones play an important role in adolescent neural and behavioural development, causing changes that can be seen throughout life. Endogenous hormones have a direct impact on behaviour in both immediate and permanent ways by acting on ...
Kulbarsh, Kyle D.
core +2 more sources
Chinese Journal of Contemporary Neurology and NeurosurgeryObjective To explore the effect and the possible mechanism of glycyrrhizin acid (GA) on the seizure onset and hippocampal neuron injury in kainic acid (KA) induced epileptic rat models.
CHEN Yan +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Unveiling the Impacts of Cashew Nuts on Oxidative Stress in Rats: A Systematic Review
AntioxidantsIntroduction: The fruit of the cashew tree, known as cashew, is accompanied by the fleshy extension of its stem, referred to as the cashew nut. Rich in phenolic compounds, such as phenolic acids, anthocyanins, flavonoids, carotenoids, polyphenols, as ...
Roque Ribeiro da Silva Júnior +15 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Dentistry JournalBackground/Objectives: Rapid palatal expansion is commonly used to correct maxillary deficiencies. However, medications like Isotretinoin may influence bone remodeling during treatment. Isotretinoin, a drug used to treat acne, was the focus of this study,
Maria Júlia Bento Martins Parreira +9 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Memory changes in rats following repeated blast-induced neurotrauma
Zaporožskij Medicinskij ŽurnalAim. To determine the characteristics of memory changes in associative and spatial memory in the dynamics of repeated blast-induced neurotrauma (rBINT) in rats. Materials and methods.
V. O. Chaban, Yu. V. Kozlova
doaj +1 more source