Results 71 to 80 of about 2,146 (159)

Case Report: Fulminant meningococcus-meningitis under treatment with ravulizumab despite complete vaccination—a rare but severe complication

Frontiers in Medicine
ObjectivesComplement C5 inhibitors such as ravulizumab are increasingly used for acetylcholine receptor–positive generalized myasthenia gravis (MG) but confer a relevant risk of invasive meningococcal infection.
Gábor Kozák, Gábor Kozák, Stefan Förster, Michael Haap, Reimer Riessen, Samuel Böhm-Gonzalez, Jan-Hendrik Stahl, Alexander Grimm, Ulf Ziemann, Ulf Ziemann, Siri Göpel, Josua Kegele, Annerose Mengel, Annerose Mengel, Katharina Feil, Katharina Feil   +15 more
doaj   +1 more source

Assessing Preferences for Rare Disease Treatment: Qualitative Development of the Paroxysmal Nocturnal Hemoglobinuria Patient Preference Questionnaire (PNH-PPQ©)

Patient Preference and Adherence, 2020
Karen Kaiser,1 Susan E Yount,1 Christa E Martens,1 Kimberly A Webster,1 Sara Shaunfield,1 Amy Sparling,1 John Devin Peipert,1 David Cella,1 Scott T Rottinghaus,2 Bonnie MK Donato,2 Richard Wells,3 Ioannis Tomazos2 1Department of Medical Social Sciences ...
Kaiser K, Yount SE, Martens CE, Webster KA, Shaunfield S, Sparling A, Peipert JD, Cella D, Rottinghaus ST, Donato BMK, Wells R, Tomazos I   +11 more
doaj  

Translating biomarker insights into practice: a path forward in TA-TMA management

Frontiers in Medicine
Recent advances in the management of transplant-associated thrombotic microangiopathy (TA-TMA) include the harmonization of diagnostic criteria and the identification of high-risk disease features.
Sonata Jodele, Eleni Gavriilaki
doaj   +1 more source

mRNA-1273/ravulizumab [PDF]

Reactions Weekly, 2021
openaire   +1 more source

Complement C5 Inhibition and Short-Term Cardiovascular Outcomes After Acute Limb Ischemia: A Real-World Cohort Study

International Journal of Translational Medicine
Background: Acute limb ischemia (ALI) is a vascular emergency characterized by abrupt limb hypoperfusion, ischemia–reperfusion injury, and a high risk of thromboinflammatory and organ complications.
Carl Vahldieck, Benedikt Fels
doaj   +1 more source

Successful haploidentical hematopoietic stem cell transplantation for paroxysmal nocturnal hemoglobinuria with severe pancytopenia developed after long‐term aplastic anemia treatment

Clinical Case Reports
Key Clinical Message Haploidentical hematopoietic stem cell transplantation (HSCT) with posttransplant cyclophosphamide is an alternative treatment for aplastic anemia–paroxysmal nocturnal hemoglobinuria (PNH) syndrome with poor prognostic factors ...
Kazuki Sakurai, Kei Saito, Shunsuke Hatta, Yuna Katsuoka, Kuniaki Meguro, Hisayuki Yokoyama, Toru Izumi   +6 more
doaj   +1 more source

Ravulizumab for the Treatment of aHUS in Adults: Improving Quality of Life [PDF]

Kidney International Reports, 2021
Christophe Legendre, Rebecca-Sberro-Soussan, Julien Zuber   +2 more
openaire   +3 more sources

Eculizumab or ravulizumab treatment effect in people with neuromyelitis optica spectrum disorder: a plain language summary of three studies

Journal of Comparative Effectiveness Research
What is this summary about? Neuromyelitis optica spectrum disorder (NMOSD for short) is a rare autoimmune health condition, meaning that the body’s natural defense system (the immune system) attacks the body’s own tissues.
Alfredo Damasceno, Mariano Marrodan
doaj   +1 more source

Long-Term Ravulizumab Efficacy and Safety in AQP4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder: Final CHAMPION-NMOSD Results. [PDF]

Neurol Neuroimmunol Neuroinflamm
Pittock SJ, Barnett MH, Bennett JL, Berthele A, de Sèze J, Levy M, Nakashima I, Oreja-Guevara C, Palace J, Paul F, Pozzilli C, Pathak R, Allen K, Parks B, Kim HJ.   +14 more
europepmc   +1 more source

Influenza A(H1N1) triggered atypical hemolytic uremic syndrome in a child with homozygous CD46 variant successfully treated with ravulizumab: a case report. [PDF]

CEN Case Rep
Mazzillo Vega L, Montero Zambrano AC, Luna Mazzillo A.   +2 more
europepmc   +1 more source