Results 241 to 250 of about 5,986,284 (284)

Different Cellular Effects of Platinum Nanoparticles on RAW 264.7 Cells

Journal of Nanoscience and Nanotechnology, 2019
The cellular effects of platinum nanoparticle (PtNP) and platinum nanocolloid (PtNC) were investigated on murine leukemia Raw 264.7 cells. PtNP induced strong cytotoxic effects on Raw 264.7 cells while PtNC showed only mild cytotoxicity. Dramatic reduction in cell growth and morphological changes were observed for cells treated with PtNPs while PtNC ...
Ta Thi, Loan, Le Thanh, Do, Hoon, Yoo
openaire   +2 more sources

Formation and stability ofS-nitrosothiols in RAW 264.7 cells

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2004
S-Nitrosothiols have been suggested to be mediators of many nitric oxide-dependent processes, including apoptosis and vascular relaxation. Thiol nitrosation is a poorly understood process in vivo, and the mechanisms by which nitric oxide can be converted into a nitrosating agent have not been established.
Yanhong, Zhang, Neil, Hogg
openaire   +2 more sources

Cytotoxic and Apoptotic Impacts of Ceranib-2 on RAW 264.7 Macrophage Cells

Anti-Cancer Agents in Medicinal Chemistry, 2023
Background: Many ceramidase inhibitors have been developed and identified as potential treatment agents for various types of tumors in the last several decades. In recent years, their therapeutic potential against tumors has gained great attention. Inhibition of ceramidase is r eportedly related to apoptosis and cytotoxicity in macrophages, which are ...
filiz Susuz Alanyalı, Osman Algı
openaire   +2 more sources

Cytotoxicity of lambda-cyhalothrin on the macrophage cell line RAW 264.7

Journal of Environmental Sciences, 2010
The wide use and wide-spectrum toxicity of synthetic pyrethroids (SPs) insecticides make them an emerging ecotoxicological concern. Some previous studies showed that SPs possessed cytotoxicity in some immune cells such as human lymphocytes and rat bone marrow.
Quan, Zhang, Cui, Wang, Liwei, Sun, Ling, Li, Meirong, Zhao   +4 more
openaire   +2 more sources

Effects of UTP on Viability in RAW 264.7 Cell Line

2022
Macrophages are important cells of immune system and their deficiency or dysfunction lead to severe diseases. Uridine-5’-triphosphate, a pyrimidine nucleotide, is known to behave as a signaling molecule for macrophages. However, the effect of UTP on macrophage viability or proliferation is yet to be researched. Therefore, we investigated the effects of
ERMİŞ, Erkan, CANSEV, Zeynep, ETGÜ, Onur, YÖYEN ERMİŞ, Diğdem, ORAL, Barbaros   +4 more
openaire   +3 more sources

Platinum Nanoparticles Induce Apoptosis on Raw 264.7 Macrophage Cells

Journal of Nanoscience and Nanotechnology, 2018
The cellular effects of platinum nanoparticles (PNP05, average size of 5 nm, and PNP30, average size of 30 nm) were investigated on murine leukemia Raw 264.7 cells. Cells treated with various concentrations of PNPs showed size-dependent cytotoxicity in an MTT assay with PNP5 of smaller nanoparticles higher toxicity than PNP30.
Ta Thi, Loan, Le Thanh, Do, Hoon, Yoo
openaire   +2 more sources

Palmitate induces RIP1-dependent necrosis in RAW 264.7 cells

Atherosclerosis, 2012
The kinase receptor-interacting protein (RIP) 1, a serine/threonine protein kinase, is a key signaling molecule for necrosis. The possible involvement of RIP1 in palmitate-induced macrophage death and its underlying molecular mechanism was investigated in this study.Cell viability was measured by an MTT reduction assay.
Seong Keun, Kim, Gimoon, Seo, Eunhye, Oh, Song-Hyo, Jin, Gue Tae, Chae, Seong-Beom, Lee   +5 more
openaire   +2 more sources

Effect of wear-debris particles on RAW 264.7 cells

Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference (NEBEC), 2010
Wear-debris particles from ultrahigh molecular weight polyethylene (UHMWPE) and metals has been implicated in periprosthetic osteolysis and cellular response to them depend on their size and dose. Response to larger particles has been previously studied, but there are no specific studies examining biological response to simultaneous administration of ...
M. K. Musib, S. Saha
openaire   +1 more source

AP-1 stimulates the cathepsin K promoter in RAW 264.7 cells

Gene, 2007
Cathepsin K (CTSK) is a secreted protease that plays an essential role in osteoclastic bone resorption, and CTSK levels increase with osteoclast differentiation and activation, a process that is controlled by a complex physiological network of hormones and cytokines. A critical regulator of this process is receptor activator of NF-kappaB ligand (RANKL),
Manhui, Pang, Ariel F, Martinez, Isabel, Fernandez, Wayne, Balkan, Bruce R, Troen   +4 more
openaire   +2 more sources

In vitro immunotoxic evaluation of herbicides in RAW 264.7 cells

Journal of Toxicology and Environmental Health, Part A
Weeds are a concern in agriculture and the use of herbicides constitutes an effective, efficient, and economical way to control their growth. Recent discoveries of herbicides are promising for the management of resistant weeds. However, there is a gap in the knowledge of the toxic effects of some herbicides previously reported on immune cells.
Larissa Vivan, Cestonaro, Aline Mocellin, Conte, Fernanda Capitanio, Goldoni, Nara Lins Meira, Quintão, Solange Cristina, Garcia, José Roberto, Santin, Marcelo Dutra, Arbo   +6 more
openaire   +2 more sources