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Scalable and unsupervised discovery from raw sequencing reads using SPLASH2

Nature Biotechnology
We introduce SPLASH2, a fast, scalable implementation of SPLASH based on an efficient k-mer counting approach for regulated sequence variation detection in massive datasets from a wide range of sequencing technologies and biological contexts. We demonstrate biological discovery by SPLASH2 in single-cell RNA sequencing (RNA-seq) data and in bulk RNA-seq
Marek Kokot   +4 more
openaire   +3 more sources

lamassemble: Multiple Alignment and Consensus Sequence of Long Reads

Methods in Molecular Biology, 2021
Martin C Frith   +2 more
exaly   +2 more sources

Macaca mulatta Raw sequence reads

2021
10 Macaca mulatta samples' with diarrhea Raw RNA sequence ...
openaire   +1 more source

Solanum aethiopicum Raw sequence reads

2019
S. aethiopicum is a close relative to S. melongena and has been routinely used to improve disease resistance in S. melongena. However, these efforts have been greatly limited by the lack of a reference genome and the clear understanding of the genes involved during biotic and abiotic stress response.
openaire   +1 more source

Helicobacter pylori Raw sequence reads

2017
Helicobacter pylori, previously Campylobacter pylori, is a gram-negative, microaerophilic bacterium found usually in the stomach. It was identified in 1982 by Australian scientists Barry Marshall and Robin Warren, who found that it was present in a person with chronic gastritis and gastric ulcers, conditions not previously believed to have a microbial ...
openaire   +1 more source

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