Results 11 to 20 of about 487,788 (325)
FASTQuick: rapid and comprehensive quality assessment of raw sequence reads [PDF]
GigaScience, 2021 Abstract Background Rapid and thorough quality assessment of sequenced genomes on an ultra-high-throughput scale is crucial for successful large-scale genomic studies. Comprehensive quality assessment typically requires full genome alignment, which costs a substantial amount of computational ...
Fan Zhang, Hyun Min Kang
exaly +8 more sources
REPdenovo: Inferring De Novo Repeat Motifs from Short Sequence Reads [PDF]
PLoS ONE, 2016 Repeat elements are important components of eukaryotic genomes. One limitation in our understanding of repeat elements is that most analyses rely on reference genomes that are incomplete and often contain missing data in highly repetitive regions that ...
Chong Chu, Rasmus Nielsen, Yufeng Wu
exaly +5 more sources
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires [PDF]
Bioinformatics, 2014 Abstract Summary: Driven by dramatic technological improvements, large-scale characterization of lymphocyte receptor repertoires via high-throughput sequencing is now feasible. Although promising, the high germline and somatic diversity, especially of B-cell immunoglobulin repertoires, presents challenges for analysis requiring the ...
Jason A Vander Heiden +2 more
exaly +4 more sources
A direct comparison of the KB™ Basecaller and
BMC Research Notes, 2010 Background Relatively recently, the software KB™ Basecaller has replaced phred for identifying the bases from raw sequence data in DNA sequencing employing dideoxy chemistry. We have measured quantitatively the consequences of that change.
Jiang Hui +3 more
doaj +3 more sources
Science Progress, 2022 Due to the rapid development of NGS technologies, a huge amount of NGS raw reads have been accumulated in public repositories, such as the Short Read Archive of NCBI.
Jongsun Park, Jungmo Lee, Jonghyun Park
doaj +2 more sources
Rapid multi-locus sequence typing direct from uncorrected long reads using Krocus [PDF]
PeerJ, 2018 Genome sequencing is rapidly being adopted in reference labs and hospitals for bacterial outbreak investigation and diagnostics where time is critical.
Andrew J. Page, Jacqueline A. Keane
doaj +3 more sources
Inference of phylogenetic trees directly from raw sequencing reads using Read2Tree
Nature Biotechnology, 2023 AbstractCurrent methods for inference of phylogenetic trees require running complex pipelines at substantial computational and labor costs, with additional constraints in sequencing coverage, assembly and annotation quality, especially for large datasets.
David Dylus +4 more
openaire +6 more sources
Data in Brief, 2021 Next-generation sequences (NGS) dataset of nanobody (Nb) clones in a phage display library (PDL) is of immense value as it serves in many different ways, such as: i). estimating the library size, ii).
Somesh Banerjee +4 more
doaj +2 more sources
Genomics, Proteomics & Bioinformatics, 2017 With the rapid development of sequencing technologies towards higher throughput and lower cost, sequence data are generated at an unprecedentedly explosive rate.
Yanqing Wang +22 more
doaj +2 more sources
SPLASH2 provides ultra-efficient, scalable, and unsupervised discovery on raw sequencing reads
bioRxiv, 2023 Abstract SPLASH is an unsupervised, reference-free, and unifying algorithm that discovers regulated sequence variation through statistical analysis of k -mer composition, subsuming many application-specific methods.
Marek Kokot +4 more
openaire +3 more sources