Results 91 to 100 of about 1,081,959 (292)

Simulation Study of Optical Band Radiation during the Afterglow Phase of Gamma-Ray Bursts Based on the HADAR Experiment

open access: yesThe Astrophysical Journal
Studying the afterglow of gamma-ray bursts (GRBs) is essential for refining theoretical models, uncovering their underlying physical processes, and exploring potential new physics. Multiwavelength investigations have emerged as a fundamental approach for
Heng-Jiao Liu   +20 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Body pigmentation and meristic characteristics of Balkan golden loach (Sabanejewia balcanica) from the water catchment area of the river Sava

open access: yesCroatian Journal of Fisheries, 2018
The taxonomic research of eight populations of Sabanejewia balcanica from the water catchment area of the river Sava included the analysis of the meristic characteristics and pigmentation of their bodies.
Bajrić Alen   +4 more
doaj   +1 more source

Gamma Ray Astronomy with Magnetized Zevatrons

open access: yes, 2005
Nearby sources of cosmic rays up to a ZeV(=10^21 eV) could be observed with a multi-messenger approach including secondary gamma-rays and neutrinos. If cosmic rays above ~10^18 eV are produced in magnetized environments such as galaxy clusters, the flux ...
Armengaud, Eric   +2 more
core   +1 more source

High Energy Gamma Rays [PDF]

open access: yes, 2004
The Very High Energy Gamma Ray Astronomy (VHE) is a rapidly evolving branch of modern astronomy, which covers the range from about 50 GeV to several tens of TeV from the ground.
de Naurois, Mathieu
core   +2 more sources

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Influence of the Level of the Middle River Negro in the Amazon, Brazil, on the Properties of the Blood of the Cururu Freshwater Stingray Potamotrygon wallacei

open access: yesLimnological Review
Amazonian fishes, as an adaptive form to the annual flood cycle, develop physiological strategies to adjust to variations in their habitats. The results of this study help to understand how freshwater stingrays adapt to changes in river levels and allow ...
Adriano Teixeira de Oliveira   +9 more
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Understanding women’s and men’s perspectives on cervical cancer screening in Uganda: a qualitative study

open access: yesBMC Cancer
Background Cervical cancer remains a significant but preventable threat to women’s health throughout much of the developing world, including Uganda. Cervical cancer screening and timely treatment of pre-cancerous lesions is a cost-effective means of ...
Kathryn Bouskill   +9 more
doaj   +1 more source

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