Results 71 to 80 of about 411,008 (315)

Jupiter as a giant cosmic ray detector [PDF]

open access: yes, 2014
All authors highlight financial support of the European Community under the FP7 by an ERC starting grant.We explore the feasibility of using the atmosphere of Jupiter to detect ultra-high-energy cosmic rays (UHECRs).
Rimmer, P.B., Stark, C.R., Helling, C.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Gastrointestinal Helminthofauna of Mediterranean Elasmobranchs

open access: yesJournal of Marine Science and Engineering
Elasmobranchs (Chondrichthyes, Elasmobranchii) are exposed to a variety of gastrointestinal parasites acquired through the ingestion of infected prey. An increasing amount of evidence suggests the usefulness of parasitological information to elucidate ...
Perla Tedesco   +7 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Use in plant breeding of acute, chronic or fractionated doses of X-rays or fast neutrons as illustrated with leaves of Saintpaulia [PDF]

open access: yes, 1971
The parameters used were survival of irradiated leaves of S. ionantha , production of adventitious plantlets at the base of the petiole and mutation frequency.The differences between unfiltered X-rays from a 250/25 deep therapy apparatus and fast ...
Broertjes, C.
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Very high energy cosmic gamma rays from radio and x-ray pulsars [PDF]

open access: yes, 1987
This thesis is concerned with the detection of very high energy cosmic gamma-rays from isolated pulsars and X-ray binary sources using the atmospheric Cerenkov technique. A general introduction to gamma ray detection techniques is followed by adscription
Chadwick, P.M, Chadwick, Mary Paula
core  

Simulation Study of Optical Band Radiation during the Afterglow Phase of Gamma-Ray Bursts Based on the HADAR Experiment

open access: yesThe Astrophysical Journal
Studying the afterglow of gamma-ray bursts (GRBs) is essential for refining theoretical models, uncovering their underlying physical processes, and exploring potential new physics. Multiwavelength investigations have emerged as a fundamental approach for
Heng-Jiao Liu   +20 more
doaj   +1 more source

Glenohumeral Passive Range of Motion and the Correlation to Shoulder Injuries in Professional Baseball Pitchers

open access: yesOrthopaedic Journal of Sports Medicine, 2013
Objectives: Glenohumeral internal rotation deficit (GIRD) indicates a 20 degree or greater loss of IR on the throwing shoulder compared to the non-throwing shoulder.
Kevin E. Wilk PT, DPT   +6 more
doaj   +1 more source

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