Results 61 to 70 of about 1,089,305 (292)
, 2013 IceCube experiment has detected two neutrinos with energies beween 1-10 PeV. They might have originated from Galactic or extragalactic sources of cosmic rays.
Gupta, Nayantara
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Journal of Forest Science, 2008 The aim of this study was to compare the structure of beech juvenile and mature wood in relation to wood density. The comparative analysis between juvenile and mature wood examined the diameter of vessels, the width and height of pith rays, and the ...
V. Gryc +3 more
doaj +1 more source
Cosmic-Ray Induced Diffuse Emissions from the Milky Way and Local Group Galaxies
, 2011 Cosmic rays fill up the entire volume of galaxies, providing an important source of heating and ionisation of the interstellar medium, and may play a significant role in the regulation of star formation and galactic evolution.
Abdo +5 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The Astrophysical JournalStudying the afterglow of gamma-ray bursts (GRBs) is essential for refining theoretical models, uncovering their underlying physical processes, and exploring potential new physics. Multiwavelength investigations have emerged as a fundamental approach for
Heng-Jiao Liu +20 more
doaj +1 more source
Gastrointestinal Helminthofauna of Mediterranean Elasmobranchs
Journal of Marine Science and EngineeringElasmobranchs (Chondrichthyes, Elasmobranchii) are exposed to a variety of gastrointestinal parasites acquired through the ingestion of infected prey. An increasing amount of evidence suggests the usefulness of parasitological information to elucidate ...
Perla Tedesco +7 more
doaj +1 more source
Orthopaedic Journal of Sports Medicine, 2013 Objectives: Glenohumeral internal rotation deficit (GIRD) indicates a 20 degree or greater loss of IR on the throwing shoulder compared to the non-throwing shoulder.
Kevin E. Wilk PT, DPT +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source