Results 61 to 70 of about 411,008 (315)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Relation between mutation yield and cell lethality over a wide range of X-ray and fission neutron doses in maize [PDF]

, 1973
Dry maize seeds, of a genetic stock heterozygous for the yellow-green locus (Yg^ Λ ^ ) ι were irradiated with fission neutron doses up to 2700 rads and with 250 kVp X-rays to 40 000 rads.
Rossi, H. H., Kellerer, A. M., Kellerer, Albrecht M., Smith, H. H.   +3 more
core   +1 more source

COSMIC-RAYS AND GAMMA RAY BURSTS

EAS Publications Series, 2013
Cosmic-rays are subatomic particles of energies ranging between a few eV to hundreds of TeV. These particles register a power-law spectrum, and it seems that most of them originate from astrophysical galactic and extragalactic sources. The shock acceleration in superalfvenic astrophysical plasmas, is believed to be the main mechanism responsible for ...
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Fusion cross sections from measurements of delayed X-rays [PDF]

, 2019
The program XRAY is a FORTRAN 77 computer code for the extraction of fusion cross sections from delayed X-ray measurements. This is accomplished by calculating the theoretical expressions of the time dependence of the evaporation-residue cross sections ...
A.J. Pacheco (8091455), M. Elgue (8091464), D.E. Di Gregorio (8091458), J.O. Fernández Niello (8091461)   +3 more
core   +1 more source

Breast cancer survival in a rural setting in the Busoga Region of Uganda

BJC Reports
Background Breast cancer (BC) poses a significant health challenge globally. While high-income countries benefit from robust healthcare systems, sub-Saharan Africa (SSA) faces elevated BC mortality rates.
Rasmus Kallestrup, Katinka Bolette Lorentzen, John Mwayi, Joanita Mbabazi, Per Kallestrup, Troels Alnor Einarson   +5 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Gamma rays, cosmic rays and local molecular clouds. [PDF]

, 1988
SIGLEAvailable from British Library Document Supply Centre- DSC:D86636 / BLDSC - British Library Document Supply CentreGBUnited ...
Richardson, K.M, Richardson, K.M.
core  

Milky Way globular clusters in gamma-rays [PDF]

, 2019
Data generated from the paper De Menezes, Cafardo & Nemmen 2019, "Milky Way globular clusters in gamma-rays: analysing the dynamical formation of millisecond pulsars" published in MNRAS (DOI 10.1093/mnras/stz898).
Raniere de Menezes (6706769), Rodrigo Nemmen (3134568), Fabio Cafardo (6706770)   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source