Results 81 to 90 of about 1,081,959 (292)

Pulsar-wind nebulae in X-rays and TeV gamma-rays

open access: yes, 2010
Pulsars are known to be efficient accelerators that produce copious amounts of relativistic particles and inject them into the Galactic medium. The radiation emitted by such a pulsar wind can be seen from radio through gamma-rays as a pulsar-wind nebula (
Kargaltsev, Oleg, Pavlov, George
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Trophic interactions among three elasmobranch species coexisting in the Oman Sea: implications for resource partitioning [PDF]

open access: yesبوم‌شناسی آبزیان, 2017
In this study, trophic interactions were studied among three elasmobranches including Iago omanensis, Rhinobatos punctifer and Torpedo sinuspersici coexisting in the depth ranging from 50 to 100 meters in the Oman Sea (Sistan and Balochistan waters).
Ali Reza Rastgoo, Tooraj Valinassab
doaj  

Colored ray configurations

open access: yesComputational Geometry, 2018
We study the cyclic color sequences induced at infinity by colored rays with apices being a given balanced finite bichromatic point set. We first study the case in which the rays are required to be pairwise disjoint. We derive a lower bound on the number of color sequences that can be realized from any such fixed point set and examine color sequences ...
Fabila Monroy, Ruy   +8 more
openaire   +8 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

X-Ray Flashes and X-Ray Rich Gamma Ray Bursts

open access: yes, 2006
6 pages, 3 figures (2 in color), to appear in the proceedings of the October 2000 Rome Workshop on ``Gamma-Ray Bursts in the Afterglow Era''
Heise, John   +3 more
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

COSMIC-RAYS AND GAMMA RAY BURSTS

open access: yesEAS Publications Series, 2013
Cosmic-rays are subatomic particles of energies ranging between a few eV to hundreds of TeV. These particles register a power-law spectrum, and it seems that most of them originate from astrophysical galactic and extragalactic sources. The shock acceleration in superalfvenic astrophysical plasmas, is believed to be the main mechanism responsible for ...
openaire   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

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