Results 21 to 30 of about 9,748 (50)

Identification of human papillomavirus and Rb/E2F pathway genomic alterations in mixed adeno-neuroendocrine carcinoma

Indian Journal of Pathology and Microbiology
Objective: To investigate the molecular characteristics of Rb/E2F in mixed adeno-neuroendocrine carcinoma (MANEC). Materials and Methods: The clinicopathological features of MANEC were analyzed.
Feng Ling, Zhihui Yang
doaj   +1 more source

Revisiting perfect fluid dark matter: Observational constraints from our galaxy

Physics Letters B, 2016
We revisit certain features of an assumed spherically symmetric perfect fluid dark matter halo in the light of the observed data of our galaxy, the Milky Way (MW). The idea is to apply the Faber–Visser approach of combined observations of rotation curves
Alexander A. Potapov, Guzel M. Garipova, Kamal K. Nandi   +2 more
doaj   +1 more source

Prediction of Non-Response to Neoadjuvant Chemoradiotherapy in Esophageal Cancer Patients with ¹⁸F-FDG PET Radiomics Based Machine Learning Classification

Diagnostics, 2022
Background: Approximately 26% of esophageal cancer (EC) patients do not respond to neoadjuvant chemoradiotherapy (nCRT), emphasizing the need for pre-treatment selection.
Roelof J. Beukinga, Floris B. Poelmann, Gursah Kats-Ugurlu, Alain R. Viddeleer, Ronald Boellaard, Robbert J. De Haas, John Th. M. Plukker, Jan Binne Hulshoff   +7 more
doaj   +1 more source

Pharmacogenetic Profiling of Allogeneic Stem Cell Transplantation Patients: An Exploratory Descriptive Study

Hemato
Background/Objectives: Patients receiving allogeneic hematopoietic stem cell transplantation (alloHCT) for acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) are at high risk for severe disease and treatment-related complications and ...
Lea P. A. Timmann, Pauline Lanting, Linde M. Morsink, Marcel Nijland, Laura B. Bungener, Gerwin A. Huls, Daan J. Touw, Thijs H. Oude Munnink, Carolien M. Woolthuis   +8 more
doaj   +1 more source

Survey response in colorectal surgery. A systematic review

Surgery in Practice and Science, 2022
Background: Survey research is widely used for developing value-based management strategies in colorectal surgery. However, declining response rates threaten the validity of results.
Vincent M. Meyer, Stan Benjamens, Joost Keupers, Louise B.D. Banning, Robert A. Pol, Johan F.M. Lange   +5 more
doaj   +1 more source

The natural history of progressive myoclonus ataxia

Neurobiology of Disease
Progressive myoclonus ataxia (PMA) is a rare clinical syndrome characterized by the presence of progressive myoclonus and ataxia, and can be accompanied by mild cognitive impairment and infrequent epileptic seizures.
Sterre van der Veen, Hendriekje Eggink, Jan Willem J. Elting, Deborah Sival, Corien C. Verschuuren-Bemelmans, Tom J. de Koning, Marina A.J. Tijssen   +6 more
doaj   +1 more source

Limitations of Semi-Automated Immunomagnetic Separation of HLA-G-Positive Trophoblasts from Papanicolaou Smears for Prenatal Genetic Diagnostics

Diagnostics
Background: In prenatal genetic diagnostics, the detection of single-gene defects relies on chorionic villus sampling (CVS) and amniocentesis, which carry a miscarriage risk of 0.2–0.3%. To mitigate this risk, fetal trophoblasts have been isolated from a
Eddy N. de Boer, Nicole Corsten-Janssen, Elles Wierenga, Theo Bijma, Jurjen T. Knapper, Gerard J. te Meerman, Gwendolyn T. R. Manten, Nine V. A. M. Knoers, Katelijne Bouman, Leonie K. Duin, Cleo C. van Diemen   +10 more
doaj   +1 more source

Emotion Recognition in Patients with Low-Grade Glioma before and after Surgery

Brain Sciences, 2022
Research on patients with low-grade gliomas (LGGs) showed neurocognitive impairments in various domains. However, social cognition has barely been investigated.
Anne M. Buunk, Marleen J. J. Gerritsen, Hanne-Rinck Jeltema, Michiel Wagemakers, Jan D. M. Metzemaekers, Rob J. M. Groen, Jacoba M. Spikman   +6 more
doaj   +1 more source

Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer

Clinical and Developmental Immunology, 2010
The prognosis of epithelial ovarian cancer (EOC), the primary cause of death from gynaecological malignancies, has only modestly improved over the last decades.
Renee Vermeij, Toos Daemen, Geertruida H. de Bock, Pauline de Graeff, Ninke Leffers, Annechien Lambeck, Klaske A. ten Hoor, Harry Hollema, Ate G. J. van der Zee, Hans W. Nijman   +9 more
doaj   +1 more source

Early Onset Ataxia with Comorbid Dystonia: Clinical, Anatomical and Biological Pathway Analysis Expose Shared Pathophysiology

Diagnostics, 2020
In degenerative adult onset ataxia (AOA), dystonic comorbidity is attributed to one disease continuum. However, in early adult onset ataxia (EOA), the prevalence and pathogenesis of dystonic comorbidity (EOAD+), are still unclear.
Deborah A. Sival, Martinica Garofalo, Rick Brandsma, Tom A. Bokkers, Marloes van den Berg, Tom J. de Koning, Marina A. J. Tijssen, Dineke S. Verbeek   +7 more
doaj   +1 more source