Identification of potentially actionable genetic variants in epithelial ovarian cancer: a retrospective cohort study. [PDF]
NPJ Precis OncolOvarian cancer is the most lethal gynecologic malignancy, mainly due to late-stage diagnosis, frequent recurrences, and eventually therapy resistance.
Fieuws C +9 more
europepmc +2 more sources
How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation. [PDF]
PLoS Computational Biology, 2013 Osteosarcomas (OS) are complex bone tumors with various genomic alterations. These alterations affect the expression and function of several genes due to drastic changes in the underlying gene regulatory network.
Kathrin Poos +5 more
doaj +1 more source
Diagnostic Pathology, 2021 Background Quick and reliable testing of EGFR and KRAS is needed in non-small cell lung cancer (NSCLC) to ensure optimal decision-making for targeted therapy.
Saskia Offerman +5 more
doaj +1 more source
Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases
Inflammation and Regeneration, 2021 T follicular helper cells participate in stimulating germinal center (GC) formation and supporting B cell differentiation and autoantibody production. However, T follicular regulatory (Tfr) cells suppress B cell activation.
He Hao +2 more
doaj +1 more source
Upregulated Neuro-oncological Ventral Antigen 1 (NOVA1) Expression Is Specific to Mature and Immature T- and NK-Cell Lymphomas [PDF]
Journal of Pathology and Translational Medicine, 2016 Background: Recent studies have revealed that the splicing factor neuro-oncological ventral antigen 1 (NOVA1) is enriched in fibroblasts and accumulated T cells of tertiary lymphoid structures.
Eun Kyung Kim +5 more
doaj +1 more source
The Potential Roles of MELF-Pattern, Microvessel Density, and VEGF Expression in Survival of Patients with Endometrioid Endometrial Carcinoma: A Morphometrical and Immunohistochemical Analysis of 100 Cases [PDF]
Journal of Pathology and Translational Medicine, 2017 Background In this study, we hypothesized that microcystic, elongated, fragmented (MELF)-pattern, vascular endothelial growth factor (VEGF) expression by cancer cells and microvessel density of cancer stroma may be associated with progression of ...
Dmitry Aleksandrovich Zinovkin +4 more
doaj +1 more source
Current Cytology Practices in Korea: A Nationwide Survey by the Korean Society for Cytopathology [PDF]
Journal of Pathology and Translational Medicine, 2017 Background Limited data are available on the current status of cytology practices in Korea. This nationwide study presents Korean cytology statistics from 2015.
Eun Ji Oh +7 more
doaj +1 more source
Korean Red Ginseng extract induces angiogenesis through activation of glucocorticoid receptor
Journal of Ginseng Research, 2017 Background: Our previous studies have demonstrated that ginsenoside-Rg1 can promote angiogenesis in vitro and in vivo through activation of the glucocorticoid receptor (GR).
Wai-Nam Sung +4 more
doaj +1 more source
Rectal Invasion by Prostatic Adenocarcinoma That Was Initially Diagnosed in a Rectal Polyp on Colonoscopy [PDF]
Journal of Pathology and Translational Medicine, 2019 Despite anatomical proximity, prostatic adenocarcinoma with rectal invasion is extremely rare. We present a case of rectal invasion by prostatic adenocarcinoma that was initially diagnosed from a rectal polyp biopsied on colonoscopy in a 69-year-old ...
Ghilsuk Yoon, Man-Hoon Han, An Na Seo
doaj +1 more source
Electrogenicity accompanies photoreduction of the iron-sulfur clusters FA and FB in photosystem I [PDF]
, 1998 Photovoltage responses accompanying electron transfer on the acceptor side of photosystem I (PS I) were investigated in proteoliposomes containing PS I complexes from the cyanobacterium Synechococcus sp. PCC 6301 using a direct electrometrical technique.
Brettel +23 more
core +2 more sources