Cytogenomic Abnormalities in Children With Acute Lymphoblastic Leukemia From Western Mexico: A Single-Center Fluorescence In Situ Hybridization-Based Study. [PDF]
EJHaemABSTRACT Introduction In Mexico, the 5‐year overall survival (OS) rate for pediatric acute lymphoblastic leukemia (ALL) ranges from 45% to 85%, markedly lower than the ∼90% reported in high‐income countries, where cytogenomic testing is essential for accurate risk stratification and therapeutic decision‐making.
Arreola RMG +8 more
europepmc +2 more sources
How microRNA and transcription factor co-regulatory networks affect osteosarcoma cell proliferation. [PDF]
PLoS Computational Biology, 2013 Osteosarcomas (OS) are complex bone tumors with various genomic alterations. These alterations affect the expression and function of several genes due to drastic changes in the underlying gene regulatory network.
Kathrin Poos +5 more
doaj +1 more source
Completing the view – histologic insights from circular AAA specimen including 3D imaging
Diagnostic Pathology, 2023 Abdominal aortic aneurysm (AAA) is a pathologic enlargement of the infrarenal aorta with an associated risk of rupture. However, the responsible mechanisms are only partially understood.
Anna-Leonie Menges +15 more
doaj +1 more source
Analysis of immunophenotypic features in hyaline vascular type Castleman disease
Diagnostic Pathology, 2023 Background Studies suggested that the immunophenotype of hyaline vascular type Castleman disease (HVCD) lacked characteristics, which was easy to be confused with other diseases. Methods From January 2010 to June 2022, 17 cases of HVCD were selected from
Yu Chang, Yu Ma, Chen Chang, Wensheng Li
doaj +1 more source
Korean Red Ginseng extract induces angiogenesis through activation of glucocorticoid receptor
Journal of Ginseng Research, 2017 Background: Our previous studies have demonstrated that ginsenoside-Rg1 can promote angiogenesis in vitro and in vivo through activation of the glucocorticoid receptor (GR).
Wai-Nam Sung +4 more
doaj +1 more source
Tumor Cell Plasticity in Cancer: Signaling Pathways and Pharmaceutical Interventions. [PDF]
MedComm (2020)Cell plasticity refers to a dynamic program through which cells reprogram their phenotype, acquiring new histologic and molecular characteristics. Recognized as a hallmark of cancer, cellular plasticity plays a critical role in tumor evolution.
Sun S +7 more
europepmc +2 more sources
Electrogenicity accompanies photoreduction of the iron-sulfur clusters FA and FB in photosystem I [PDF]
, 1998 Photovoltage responses accompanying electron transfer on the acceptor side of photosystem I (PS I) were investigated in proteoliposomes containing PS I complexes from the cyanobacterium Synechococcus sp. PCC 6301 using a direct electrometrical technique.
Brettel +23 more
core +2 more sources
Vulvar squamous cell carcinoma with sarcoma-like stroma: A case report and review of the literature
Diagnostic Pathology, 2011 Vulvar squamous cell carcinoma with sarcoma-like stroma represents an extremely rare histological entity showing the co-existence of both epithelial and mesenchymal features: these tumors, firstly described in the skin by Martin and Stewart in 1935 have ...
Macchia Gabriella +4 more
doaj +1 more source
Ionic basis of a mechanotransduction current in adult rat dorsal root ganglion neurons
Molecular Pain, 2006 Sensory mechanical transduction – necessary for hearing, proprioception, and the senses of touch and pain – remains poorly understood. In somatosensation, even the basic properties of the mechanically sensitive excitatory ionic currents that are assumed ...
McCarter Gordon C, Levine Jon D
doaj +1 more source
Diagnostic Pathology, 2008 Background Pseudosarcomatous myofibroblastic lesions of the urinary bladder are relatively rare entities of an uncertain pathogenesis and benign indolent nature.
Deliveliotis Charalambos +7 more
doaj +1 more source