Results 21 to 30 of about 28,464 (119)
Treated Choroidal Melanoma with Late Metastases to the Contralateral Orbit
Choroidal melanoma is the commonest adult primary intraocular tumour, 1 and usual sites of secondary spread are to liver, bone and lung. Although delayed recurrence of ipsilateral orbital melanoma is well documented, metastasis to the contralateral orbit
Sonia George+4 more
doaj +1 more source
Whole-exome sequencing reveals the etiology of the rare primary hepatic mucoepidermoid carcinoma
Background Primary hepatic mucoepidermoid carcinoma (HMEC) is extremely rare and the molecular etiology is still unknown. The CRTC1-MAML2 fusion gene was previously detected in a primary HMEC, which is often associated with MEC of salivary gland in the ...
Ping Hou+9 more
doaj +1 more source
Osteochondrogenesis derived from synovial fibroblasts in inflammatory arthritis model
Rheumatoid arthritis (RA) is characterized by chronic joint inflammation, which forms pannus with bone destruction. Bony ankylosis is also observed following inflammation; however, the mechanism behind this aberrant bone formation in RA had remained ...
Yoko Miura, Satoshi Kanazawa
doaj +1 more source
Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals
One‐third of the world's population is affected by metabolic syndrome. Complicated pathogenesis and limited drugs cause the growing prevalence of metabolic syndrome. Macrophage‐mediated metaflammation is closely associated with the development of metabolic syndrome. The role of phytochemicals targeting macrophages in the treatment of metabolic syndrome
Zeting Ye+6 more
wiley +1 more source
The changes of Coagulation State in Patients Contracted with SARS-COV-19 [PDF]
Coronaviruses are considered to be one of the most significant human and animal pathogens. In late 2019, a new species of coronavirus was recognized as the cause of some pneumonia cases in Wuhan, China.
Anahita Nosrati
doaj +1 more source
ABSTRACT Background Genetic testing and sequencing technologies offer a comprehensive understanding of cancer genetics, providing rapid and cost‐effective solutions. In particular, these advanced technologies play an important role in assessing the complexities of the rare cancer types affecting several systems including the bone, endocrine, digestive,
Joviana Farhat+4 more
wiley +1 more source
Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation [PDF]
Background & Objective: Cervical cancer is the most common cancer in women worldwide with high mortality, necessitating quicker diagnostic methods. We wish to enhance the existing cervical biopsies of Squamous Intraepithelial Lesions (SIL) using p16 and ...
Apurv Ghosh+3 more
doaj +1 more source
Pancreatic Cancer: Pathogenesis and Clinical Studies
Although the treatment landscape for cancer has evolved rapidly in recent years, progress has stagnated for pancreatic cancer (PC). PC includes multiple types, but pancreatic ductal adenocarcinoma (PDAC) accounts for >90% of cases. This review focuses on the molecular pathogenesis and different treatments for PDAC, hoping to propose future directions ...
Kexun Zhou+3 more
wiley +1 more source
Thalassemia is a globin gene disorder that results in a diminished rate of synthesis of one or more of the globin chains. About 1.5% of the global population (80 to 90 million people) are carriers of beta Thalassemia.
R Jha, S Jha
doaj +1 more source
Overexpression of MicroRNA-506 in Jurkat (acute T Cell Leukemia) Cell Line [PDF]
Background & Objective: Acute lymphoblastic leukemia (ALL) is a malignant disease that arises from various mutations in B or T-lymphoid progenitors. MicroRNAs (miRNAs) regulate gene expression by binding to the 3' untranslated region of protein-coding ...
Shaghayegh Rostami Yasuj+4 more
doaj +1 more source