Results 81 to 90 of about 39,925 (149)

Associations between Blood Donors, Component Modifications, and the Alloimmunization of Transfusion Recipients

BACKGROUND: Prior studies have evaluated transfusion recipient variables impacting red blood cell (RBC) alloimmunization, but few focused on potentially modifiable blood donor or blood component variables.
Goel, Ruchika, Tormey, Christopher, Spencer, Bryan R., Karafin, Matthew S., Hauser, Ronald G., Yu, Han, Hendrickson, Jeanne E.   +6 more
core   +1 more source

Red blood cell alloimmunization among transfusion-dependent thalassemia major patients in Northeastern Iran

Asian Journal of Transfusion Science
BACKGROUND: Thalassemia is one of the most common congenital hemoglobinopathies globally. Regular red blood cell (RBC) transfusion is of paramount importance in the treatment of thalassemia patients.
Leila Mobasheri, Tayyebeh Chahkandi, Amir Talebpour, Gholamreza Anani Sarab   +3 more
doaj   +1 more source

RHCE and Kell genotyping and alloimmunization profile in patients with sickle cell disease in the Federal District of Brazil

Hematology, Transfusion and Cell Therapy
Introduction: Sickle cell disease (SCD) is the most important hemoglobinopathy worldwide. The treatment often requires phenotype-matched red blood cell (RBC) transfusions, but alloimmunization to non-ABO antigens may occur in a part of the SCD patients ...
Larissa Espíndola Leite, Fábio Gonçalves da Silva, Simone Kashima, Evandra Strazza Rodrigues, Rodrigo Haddad   +4 more
doaj   +1 more source

A Case Report of Red Blood Cell Alloimmunization and Delayed Hemolytic Transfusion Reaction in a Patient with an Uncommon Phenotype in Sickle Cell Disease: Review of Diagnosis and Management

Case Reports in Hematology
A delayed hemolytic transfusion reaction (DHTR) is a potential complication for patients with sickle cell disease (SCD) who develop red blood cell (RBC) alloimmunization to foreign antigens from allogeneic transfusions, potentially resulting in life ...
Cassandra P. Wang, Denise Malicki, Courtney D. Thornburg, Sonya Martinez, Jennifer C. Yu   +4 more
doaj   +1 more source

Data_Sheet_1_Marginal Zone B Cells Induce Alloantibody Formation Following RBC Transfusion.docx

, 2018
Red blood cell (RBC) alloimmunization represents a significant immunological challenge for some patients. While a variety of immune constituents likely contribute to the initiation and orchestration of alloantibodies to RBC antigens, identification of ...
Kathryn Girard-Pierce (5980175), Connie M. Arthur (5364116), Lilian Cataldi Rodrigues (328771), Seema R. Patel (5364107), Ashley L. Bennett (5980178), Megan Fuller (5980184), Xiaoxi Zhou (288605), Sean R. Stowell (659895), Cheryl L. Maier (394709), Satheesh Chonat (5980190), David R. Gibb (5980172), Ryan P. Jajosky (5980181), Nicole H. Smith (5980193), Patricia E. Zerra (5980187), Christopher A. Tormey (5980196), Jeanne E. Hendrickson (5364113)   +15 more
core   +1 more source

Alloantibody Identification: The Importance of Temperature, Strength Reaction and Enzymes—A Practical Approach

Hematology Reports
Red blood cell (RBC) alloimmunization and antibodies formation against non-self antigens on red cells may occur after blood transfusion, pregnancies or other exposures. The RBC alloimmunization rate varies from 2% to 6% according to recent studies.
Palma Manduzio
doaj   +1 more source

Nonclassical FCGR2C haplotype is associated with protection from red blood cell alloimmunization in sickle cell disease

, 2017
Key PointsVariation in the Fcγ receptor gene cluster is associated with protection from RBC alloimmunization in patients with SCD. This association appears to be strongest for alloimmunization to antigens other than the immunogenic Rh or K.
Joep W. R. Sins, France Pirenne, Sadaf Pakdaman, Judy Geissler, Michael W. Tanck, Bart J. Biemond, Sanne M. Meinderts, Taco W. Kuijpers, Robin van Bruggen, Anita W. Rijneveld, Sietse Q. Nagelkerke, Timo K. van den Berg, Karin Fijnvandraat, Anoosha Habibi, Christine Bruggeman, Jean-Louis H. Kerkhoffs   +15 more
core   +1 more source

Blood Donor RBC Genotyping at the National Advisory Unit on Immunohematology at Oslo University Hospital

Biomedicines
Background: Blood transfusion has an essential place in the treatment of several patient groups but entails alloimmunization risk. The provision of phenotype-matched packed red blood cell concentrates (PRBCCs) is recommended for preventing ...
Inger Margit Alm, Hoyi Wong, Monica Stensrud, Geir Tomter, Mette S. Bævre, Çiğdem Akalın Akkök   +5 more
doaj   +1 more source

The impact of vaccination on RBC alloimmunization in a murine model. [PDF]

Vox Sang, 2017
Natarajan P, Santhanakrishnan M, Tormey CA, Hendrickson JE.   +3 more
europepmc   +1 more source

z-haiman/RBC-GEM: RBC-GEM 1.0.0

<p>First major release of RBC-GEM, changes will be outlined in upcoming manuscript!</p> <p><strong>Full Changelog</strong>: https://github.com/z-haiman/RBC-GEM/compare/0.3.0...1.0.0</p ...
z-haiman
core   +1 more source