Results 61 to 70 of about 201,799 (93)

Up-regulated succinylation modifications induce a senescence phenotype in microglia by altering mitochondrial energy metabolism

Journal of Neuroinflammation
The aging of the central nervous system(CNS) is a primary contributor to neurodegenerative diseases in older individuals and significantly impacts their quality of life.
Xinnan Zhao, Xiaohan Yang, Cong Du, Huimin Hao, Shuang Liu, Gang Liu, Guangyin Zhang, Kai Fan, Jianmei Ma   +8 more
doaj   +1 more source

Headache disorders: a persistent public health challenge for the under 50s

Frontiers in Neurology
IntroductionCurrently, neurological diseases has surpassed cardiovascular diseases as the primary cause of global disease burden. Among these, headache disorders are the most prevalent and have emerged as the main cause of disability in people under 50 ...
Weijian Meng, Weijian Meng, Liutao Sui
doaj   +1 more source

Insomnia and beyond - Exploring the therapeutic potential of orexin receptor antagonists

, 2014
Orexin/hypocretin neuropeptides, produced by a few thousand neurons in the lateral hypothalamus, are of critical importance for the control of vigilance and arousal of vertebrates, from fish to amphibians, birds and mammals.
Michel Alexander Steiner, Christopher J Winrow   +1 more
core   +1 more source

Reimagining the meninges from a neuroimmune perspective: a boundary, but not peripheral

Journal of Neuroinflammation
Recent advances in neuroscience have transformed our understanding of the meninges, the layers surrounding the central nervous system (CNS). Two key findings have advanced our understanding: researchers identified cranial bone marrow as a reservoir for ...
Xian Zhang, Liang Liu, Yan Chai, Jianning Zhang, Quanjun Deng, Xin Chen   +5 more
doaj   +1 more source

Elevated systemic inflammation response index is associated with poor outcomes in minor ischemic stroke

Frontiers in Neurology
ObjectivesPatients with minor ischemic stroke (MIS) have substantial disability rates at 90 days. Our study aimed to explore the association between the systemic inflammation response index (SIRI) and 3-month functional outcomes in patients with MIS ...
Jie Li, Jie Li, Ping Zhang, Ping Zhang, Hong Chen, Hong Chen, Yanfen Wang, Yanfen Wang, Yangyun Han, Chun Wang, Chun Wang, Xingyang Yi, Xingyang Yi   +12 more
doaj   +1 more source

Fatigue in Multiple Sclerosis

, 2016
Dear Readers, If you are engaged in the treatment of patients with MS (pwMS), this e-book’s aim is to offer novel insights to improve on an understanding of one of the major problems of pwMS: fatigue.
Christian Dettmers, John DeLuca
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A patient with P369S/R408Q variants in the MEFV gene presented with clinical features of Kikuchi disease and Mollaret meningitis, successfully treated with colchicine

BMC Neurology
Background This case report presents the case of a patient with P369S and R408Q variants in the MEFV gene who exhibited clinical features of Kikuchi disease and Mollaret meningitis. Furthermore, it discusses colchicine as a new potential treatment option
Hideo Handa, Atsuhiko Sugiyama, Hitoshi Kubosawa, Yuki Nakagawa, Dai Kishida, Akiyuki Uzawa, Akiyo Aotsuka, Satoshi Kuwabara   +7 more
doaj   +1 more source

Zika Virus: What Have We Learnt Since the Start of the Recent Epidemic?

, 2018
The considerable number of viral infectious disease threats that have emerged since the beginning of the 21st century have shown the need to dispose global and coordinated responses to fight properly and efficiently against them. Severe acute respiratory
Oscar D. Salomon, Luis C. Villamil-Jimenez, Jorg Heukelbach, Pedro M. Pimentel-Coelho, Paulo Henrique Rosado-de-Castro, Ruben Bueno-Mari, Juan-Carlos Saiz, Carlos H. Alencar, Paul Armstrong   +8 more
core   +1 more source

Band 2, 429 (Sammlung Friedlaender)

BAND 2, 429 (SAMMLUNG FRIEDLAENDER) Band 2, 429 (Sammlung Friedlaender) (Public Domain ...

core  

[Bell Helicopter 429 model]

, 2017
Photographs of the Bell Helicopter 429 model, held by UNT Special Collections as part of the Bell Helicopter Records. The model is dark red in color with a white slash and the number 429 in white on its side.
Merrill, Jeffery, Sylve, Joshua
core