Results 41 to 50 of about 175,090 (163)

KLF8 promotes cancer stem cell-like phenotypes in osteosarcoma through miR-429-SOX2 signaling.

Neoplasma (Bratislava), 2020
Krüppel-like factor 8 (KLF8) regulates critical gene transcription associated with different types of cancer. A novel paradigm in tumor biology suggests that the initiation and progression of osteosarcoma (OS) are driven by osteosarcoma stem cell-like ...
L. Zhang, Ping Yang, Q. Liu, J. Wang, F. Yan, L. Duan, F. Lin   +6 more
semanticscholar   +1 more source

Emerging biomarkers and frontier therapies: unveiling the role of endothelial dysfunction in cerebral small vessel disease

Frontiers in Neurology
Cerebral small vessel disease (cSVD), a major contributor to stroke, cognitive decline, and vascular dementia, accounts for around 25% of ischemic strokes and significantly impacts age-related neurological disability.
Kedi Sun, Hui Liu
doaj   +1 more source

Therapeutic potential of microRNAs in neurological disorders: mechanisms, biomarkers, and emerging therapeutic strategies [PDF]

Exploration of Neuroprotective Therapy
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a pivotal role in post-transcriptional gene regulation, influencing various biological processes such as cell division, proliferation, and apoptosis.
Sourav Pal, Subhajit Mandal
doaj   +1 more source

Identifying the Epileptic Network

, 2014
An important area of current research in epilepsy focuses on identifying the specific regions within the brain that are affected in individuals with recurring seizures. The epileptogenic process may result not only in pathology in focal cortical regions,
Mark Holmes, Don Tucker
core   +1 more source

miR-429 as biomarker for diagnosis, treatment and prognosis of cancers and its potential action mechanisms: A systematic literature review.

Neoplasma (Bratislava), 2019
miR-429 is a member of miR-200 family. Accumulated evidence has indicated that miR-429 dysregulation is involved in the epithelial-mesenchymal transition (EMT), progression, development, invasion, metastasis, apoptosis and drug resistance of a variety of
Chunmei Guo, Shuqing Liu, Ming-Zhong Sun
semanticscholar   +1 more source

MicroRNA-429 inhibits neuroblastoma cell proliferation, migration and invasion via the NF-κB pathway

Cellular & Molecular Biology Letters, 2020
MicroRNAs (miRNAs or miRs) can participate in the development and progression of neuroblastoma. Many studies have indicated that miR-429 can participate in tumor development. However, the mechanism underlying miR-429-mediated progression of neuroblastoma
Xianjun Zhou, Hong-ting Lu, Fu-jiang Li, Xiwei Hao, Lulu Han, Q. Dong, Xin Chen   +6 more
semanticscholar   +1 more source

Emerging advances in spinal cord injury: An introductory overview

Brain and Spine
Spinal cord injury (SCI) remains a devastating condition with limited treatment options. This Focus Issue highlights recent clinical and translational advances across the continuum of SCI care from prehospital coordination to novel therapeutics.
Michael G. Fehlings, Shintaro Honda, Peter Vajkoczy, Narihito Nagoshi   +3 more
doaj   +1 more source

RAAPNOTITIE 429

, 2010
onderzoeksrappor
Anscher, T.J. ten
core   +1 more source

A novel ETV6-miR-429-CRKL regulatory circuitry contributes to aggressiveness of hepatocellular carcinoma

Journal of experimental & clinical cancer research : CR, 2020
Background Tumor metastasis is one of the main causes of the high mortality of hepatocellular carcinoma (HCC). E-Twenty Six variant gene 6 (ETV6) is a strong transcriptional repressor, associated with the development and progression of tumors.
Chunmei Guo, Chao Gao, Dongting Zhao, Jiahui Li, Jinxia Wang, Xujuan Sun, Qinlong Liu, Lihong Hao, F. Greenaway, Yuxiang Tian, Shuqing Liu, Ming-Zhong Sun   +11 more
semanticscholar   +1 more source

Resolution of tonsillar herniation and syringomyelia after resection of supratentorial large meningioma

Brain and Spine
Background: Chiari malformation type I (CM1) with syringomyelia caused by supratentorial lesions is extremely rare, and the mechanism has not been well explained.
Chengjian Lou, Linkai Wang, Xiaoli Pan, Dan Xu, Yili Chen   +4 more
doaj   +1 more source