Results 41 to 50 of about 141,328 (115)

Emerging advances in spinal cord injury: An introductory overview

Brain and Spine
Spinal cord injury (SCI) remains a devastating condition with limited treatment options. This Focus Issue highlights recent clinical and translational advances across the continuum of SCI care from prehospital coordination to novel therapeutics.
Michael G. Fehlings, Shintaro Honda, Peter Vajkoczy, Narihito Nagoshi   +3 more
doaj   +1 more source

Resolution of tonsillar herniation and syringomyelia after resection of supratentorial large meningioma

Brain and Spine
Background: Chiari malformation type I (CM1) with syringomyelia caused by supratentorial lesions is extremely rare, and the mechanism has not been well explained.
Chengjian Lou, Linkai Wang, Xiaoli Pan, Dan Xu, Yili Chen   +4 more
doaj   +1 more source

Sedation and sleep safety of pimavanserin for Parkinsons’s disease psychosis: Review and exploratory analysis of clinical study data

Clinical Parkinsonism & Related Disorders
Patients with Parkinson’s disease almost uniformly experience sleep disorders. Sleep disorders have been linked to the severity of cognitive impairment, which is also a comorbidity with Parkinson’s disease psychosis (PDP).
Ana Berrio, Lambros Chrones, Victor Abler, Robert A. Hauser   +3 more
doaj   +1 more source

MiR‐429 suppresses proliferation and invasion of breast cancer via inhibiting the Wnt/β‐catenin signaling pathway

Thoracic Cancer, 2020
microRNAs (miRNAs) have been verified as molecular targets for regulating tumor proliferation, invasion, and metastasis in tumor progression. However, the relationship between miRNAs and cellular energy metabolism in breast cancer still needs to be ...
Liping Zhang, Qinghua Liu, Qingjie Mu, Dandan Zhou, Hongli Li, Baogang Zhang, C. Yin   +6 more
semanticscholar   +1 more source

The determination of the boundaries and prediction the radicality of glioblastoma resection using MRI and CT perfusion

Frontiers in Neurology
BackgroundPreoperative identification of diffuse glioma boundaries remains an unsolved problem of modern neurooncology. The main problem is the heterogeneity of the tumor being manifested by simultaneous presence of both contrast-enhancing and non ...
Rustam Talybov, Rustam Talybov, Tatiana Trofimova, Vadim Mochalov, Sergey Karasev, Vladislava Gorshkova, Tatiana Kleschevnikova, Irina Karasyova, Artem Batalov, Natalia Zakharova, Elena Gaijsina, Igor Pronin   +11 more
doaj   +1 more source

Theranostic application of miR-429 in HER2+ breast cancer

Theranostics, 2020
Human epidermal growth factor receptor 2 (HER2) is overexpressed/amplified in one third of breast cancers (BCs), and is associated with the poorer prognosis and the higher metastatic potential in BC.
C. Cava, C. Novello, C. Martelli, A. Lo Dico, L. Ottobrini, F. Piccotti, M. Truffi, F. Corsi, G. Bertoli, I. Castiglioni   +9 more
semanticscholar   +1 more source

Effects and mechanisms of a home-based action observation and motor imagery intervention on cognitive function and depression in spinal cord injury: a pilot randomized controlled trial protocol

Frontiers in Neurology
BackgroundCognitive impairment and depression frequently occur after spinal cord injury (SCI) and adversely affect functional independence and quality of life. There is a lack of research in addressing this important area in SCI rehabilitation/care.
Yule Hu, Yan Li, Ran Tao, Chun Liang Hsu, Ashley Craig, Ashley Craig, Chor Yin Lam, Turhan Kahraman, Angela Yee Man Leung   +8 more
doaj   +1 more source

Research progress of artificial intelligence in moyamoya disease

Frontiers in Neurology
Moyamoya disease (MMD), a chronic, progressive cerebrovascular disorder of unknown etiology, presents significant diagnostic and therapeutic challenges in clinical practice.
Huimin Huang, Huimin Huang, Ning Zheng, Lei Feng, Shuo Shao   +4 more
doaj   +1 more source

Switch from fingolimod to ozanimod for safety or intolerance reasons

Therapeutic Advances in Neurological Disorders
Introduction: Ozanimod is a new-generation sphingosine-1-phosphate (S1P) modulator, approved for the treatment of multiple sclerosis (MS), offering higher selectivity for S1P receptor 1 and 5 (SPR1-5), minimizing potential safety concerns related to S1P3
Elisabetta Signoriello, Giuseppe Romano, Matteo Foschi, Aurora Zanghì, Emanuele D’Amico, Roberta Fantozzi, Diego Centonze, Giacomo Lus   +7 more
doaj   +1 more source

Sphenopalatine ganglion stimulation for the treatment of trigeminal neuropathic pain

Frontiers in Neurology
IntroductionUnlike idiopathic trigeminal neuralgia, which can be treated with conventional neurosurgical methods such as microvascular decompression, radiofrequency rhizotomy of the Gasser ganglion, or stereotactic radiosurgery, trigeminal neuropathic ...
Paweł Sokal, Sara Kierońska-Siwak, Marcin Rusinek, Magdalena Jabłońska, Antoni Nehring, Oskar Puk, Damian Palus, Renata Jabłońska   +7 more
doaj   +1 more source