Results 31 to 40 of about 141,328 (115)

Female Gender Remains an Independent Risk Factor for Poor Outcome after Acute Nontraumatic Intracerebral Hemorrhage

Neurology Research International, 2013
Objective. To study whether gender influences outcome after intracerebral hemorrhage (ICH). Methods. Cohort study of 245 consecutive adults presenting to the emergency department with spontaneous ICH from January 2006 to December 2008.
Latha Ganti, Anunaya Jain, Neeraja Yerragondu, Minal Jain, M. Fernanda Bellolio, Rachel M. Gilmore, Alejandro Rabinstein   +6 more
doaj   +1 more source

Exosomes enriched by miR-429-3p derived from ITGB1 modified Telocytes alleviates hypoxia-induced pulmonary arterial hypertension through regulating Rac1 expression

Cell Biology and Toxicology
Recent studies have emphasized the critical role of Telocytes (TCs)-derived exosomes in organ tissue injury and repair. Our previous research showed a significant increase in ITGB1 within TCs.
Ruixue Qi, Yong Zhang, Furong Yan
semanticscholar   +1 more source

EPDR1, Which Is Negatively Regulated by miR-429, Suppresses Epithelial Ovarian Cancer Progression via PI3K/AKT Signaling Pathway

Frontiers in Oncology, 2021
Epithelial ovarian cancer (EOC) is the main pathological type of ovarian cancer. In this study, we found that ependymin-related 1 (EPDR1) was remarkably downregulated in EOC tissues, and low EPDR1 expression was associated with International Federation ...
Zhendan Zhao, Zhiling Wang, Pengling Wang, Shujie Liu, Yingwei Li, Xingsheng Yang   +5 more
semanticscholar   +1 more source

Development of a Non-Motor Fluctuation Assessment Instrument for Parkinson Disease

Parkinson's Disease, 2011
Patients with Parkinson disease are increasingly recognized to suffer from non-motor symptoms in addition to motor symptoms. Many non-motor symptoms fluctuate in parallel with motor symptoms and in relationship to plasma levodopa levels.
Galit Kleiner-Fisman, Rebecca Martine, Anthony E. Lang, Matthew B. Stern   +3 more
doaj   +1 more source

Circular RNA circLIFR suppresses papillary thyroid cancer progression by modulating the miR-429/TIMP2 axis

Journal of Cancer Research and Clinical Oncology
Circular RNAs (circRNAs) are increasingly recognized for their important roles in various cancers, including papillary thyroid cancer (PTC). The specific mechanisms by which the circLIF receptor subunit alpha (circLIFR, hsa_circ_0072309) influences PTC ...
Fengyuan Zhang, Jiazheng Li, Jingjing Xu, Xu-gan Jiang, Shengxia Chen, Qais Ahmad Nasser   +5 more
semanticscholar   +1 more source

MiR-429 Inhibits the Angiogenesis of Human Brain Microvascular Endothelial Cells through SNAI2-Mediated GSK-3β/β-Catenin Pathway

Computational and Mathematical Methods in Medicine, 2021
MicroRNA (miRNA) dysfunction has been confirmed as a key event of ischemic stroke appearance. This study is aimed at revealing the role of miR-429 in the angiogenesis of HBMECs.
Yameng Sun, Sheng-hao Ding, Yi-ling Fan, F. Shen, Qinglian Dong, B. Zhao, Yao-dong Pan, J. Wan   +7 more
semanticscholar   +1 more source

Resistance Exercise Training in McArdle Disease: Myth or Reality?

Case Reports in Neurological Medicine, 2018
McArdle disease is a metabolic myopathy mainly characterised by symptom onset during physical activities or isometric muscle contraction. Resistance (also termed strength) training is a type of physical exercise focusing on the use of resistance (e.g ...
Aleksandra Pietrusz, Renata S. Scalco, Ros Quinlivan   +2 more
doaj   +1 more source

LncRNA OIP5-AS1 promotes the malignancy of pancreatic ductal adenocarcinoma via regulating miR-429/FOXD1/ERK pathway

Cancer Cell International, 2020
Background Pancreatic ductal adenocarcinoma (PDAC), a subtype of pancreatic cancer, is a malignant tumor with unfavorable prognosis. Despite accumulating researches have made efforts on finding novel therapeutic methods for this disease, the underlying ...
Liping Wu, Yongcun Liu, Cheng Guo, Y. Shao   +3 more
semanticscholar   +1 more source

Emerging biomarkers and frontier therapies: unveiling the role of endothelial dysfunction in cerebral small vessel disease

Frontiers in Neurology
Cerebral small vessel disease (cSVD), a major contributor to stroke, cognitive decline, and vascular dementia, accounts for around 25% of ischemic strokes and significantly impacts age-related neurological disability.
Kedi Sun, Hui Liu
doaj   +1 more source

Therapeutic potential of microRNAs in neurological disorders: mechanisms, biomarkers, and emerging therapeutic strategies [PDF]

Exploration of Neuroprotective Therapy
MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a pivotal role in post-transcriptional gene regulation, influencing various biological processes such as cell division, proliferation, and apoptosis.
Sourav Pal, Subhajit Mandal
doaj   +1 more source