Results 11 to 20 of about 175,090 (163)

Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11

Pharmaceutical Biology, 2023
Context Ferroptosis may play an essential role in lipid peroxidation and endothelial dysfunction of aortic endothelial cells (ECs) in type 2 diabetes mellitus (T2DM) with atherosclerosis (AS).
Jianjie Rong, Chuanyong Li, Qiang Zhang, Guangfeng Zheng, Weijian Fan, Zhichang Pan, Shuming Shi   +6 more
semanticscholar   +1 more source

Exosomal miR-429 derived from adipose-derived stem cells ameliorated chondral injury in osteoarthritis via autophagy by targeting FEZ2.

International Immunopharmacology, 2023
BACKGROUND Osteoarthritis (OA) is the most prevalent musculoskeletal disease, imposing a significant public health burden. Exosomes might be an effective means of treating OA.
C. Meng, Yuyan Na, Changxu Han, Yizhong Ren, Ming Liu, Penglei Ma, R. Bai   +6 more
semanticscholar   +1 more source

Evaluation of the Expression Levels of miR-21-5p and miR-429 Genes in Biopsy Samples from Patients with Oral Squamous Cell Carcinoma

Diagnostics, 2023
Introduction: MicroRNAs (miRs) are a group of endogenous, non-coding, 18-24 nucleotide length single-strand RNAs that mediate gene expression at the post-transcriptional level through mRNA degradation or translational repression.
A. Garajei, A. Allameh, Mehdi Azadi, A. Emami, M. Atashbasteh, Melina Mostafavi, B. Ghaderi, F. Inchingolo, M. Sadeghi, SK Tadakamadla, Hady Mohammadi, J. Tadakamadla   +11 more
semanticscholar   +1 more source

Bioinformatic Analysis of miR-200b/429 and Hub Gene Network in Cervical Cancer

Biochemical Genetics, 2023
The miR-200b/429 located at 1p36 is a highly conserved miRNA cluster emerging as a critical regulator of cervical cancer. Using publicly available miRNA expression data from TCGA and GEO followed by independent validation, we aimed to identify the ...
Vaibhav Shukla, S. Mallya, D. Adiga, S. Sriharikrishnaa, Sanjiban Chakrabarty, S. P. Kabekkodu   +5 more
semanticscholar   +1 more source

The decreased expression of miR-429 in plasma exosomes after spinal cord injury inhibits neuronal apoptosis by mediating the PTEN/PI3K/Akt pathway

Annals of Translational Medicine, 2022
Background Neuronal apoptosis after spinal cord injury (SCI) leads to sensorial and motorial dysfunction. Exosomes are vesicles that contain many cellular components, including microRNA, and the role of miR-429 in plasma exosomes in this process after ...
Jiayi Huang, Chunshuai Wu, Guanhua Xu, Yue Sun, Chao Gui, Jiawei Fu, Zhiming Cui, Haiming Huang   +7 more
semanticscholar   +1 more source

miR‐200a/b/‐429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer

Molecular Oncology, 2022
Many patients with locally advanced cervical cancer experience recurrence within the radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to identify patients in need of intensified treatment.
A. Nilsen, T. Hillestad, V. Skingen, E. Aarnes, C. Fjeldbo, T. Hompland, T. S. Evensen, T. Stokke, G. Kristensen, B. Grallert, H. Lyng   +10 more
semanticscholar   +1 more source

MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis

BMC Molecular and Cell Biology, 2022
Background Hepatocellular carcinoma (HCC) is a common malignancy. Long non-coding RNAs (lncRNAs) partake in the progression of HCC. However, the role of lncRNA MAPKAPK5-AS1 in the development of HCC has not been fully clarified.
Z. Peng, Xin-ping Ouyang, Yexing Wang, Qiming Fan   +3 more
semanticscholar   +1 more source

Knockdown of circ-PVT1 inhibits the progression of lung adenocarcinoma and enhances the sensitivity to cisplatin via the miR-429/FOXK1 signaling axis

Molecular Medicine Reports, 2021
Lung cancer is one of the most prevalent cancers in China, and its incidence and morbidity remain high due to various independent factors. Lung adenocarcinoma (ADC) is the most common type of non-small cell lung carcinoma.
L. Cao, Xuefeng Zhou, Xi-wei Ding, Dongyun Gao   +3 more
semanticscholar   +1 more source

Circular RNA circRNA_0082835 promotes progression and lymphatic metastasis of primary melanoma by sponging microRNA miRNA-429

Bioengineered, 2021
To identify how circular RNA circRNA_0082835 impacts melanoma cells and lymphatic metastasis to observe whether it exerts effects through its action mechanism of sponging microRNA miR-429. Clinical baseline information was collected, and clinical samples
Yute Sun, Zuoqiong Hou, B. Luo, Chujun Li, Jinfang Liu, Jianlan Liu, Jian Tang, G. Yao   +7 more
semanticscholar   +1 more source

Berberine inhibits the proliferation, invasion and migration of endometrial stromal cells by downregulating miR-429

Molecular Medicine Reports, 2021
Endometriosis (EM) is a common gynecological disease, and its pathological process is accompanied by the migration and proliferation of uterine cells. Berberine (BBR) has been shown to exhibit antitumor activity; however, the effects of BBR on EM have ...
Yongjuan Gu, Zhi-yu Zhou
semanticscholar   +1 more source