Results 11 to 20 of about 141,328 (115)

Hydroxysafflor yellow A inhibits endothelial cell ferroptosis in diabetic atherosclerosis mice by regulating miR-429/SLC7A11

open access: yesPharmaceutical Biology, 2023
Context Ferroptosis may play an essential role in lipid peroxidation and endothelial dysfunction of aortic endothelial cells (ECs) in type 2 diabetes mellitus (T2DM) with atherosclerosis (AS).
Jianjie Rong   +6 more
semanticscholar   +1 more source

Exosomal miR-429 derived from adipose-derived stem cells ameliorated chondral injury in osteoarthritis via autophagy by targeting FEZ2.

open access: yesInternational Immunopharmacology, 2023
BACKGROUND Osteoarthritis (OA) is the most prevalent musculoskeletal disease, imposing a significant public health burden. Exosomes might be an effective means of treating OA.
C. Meng   +6 more
semanticscholar   +1 more source

Evaluation of the Expression Levels of miR-21-5p and miR-429 Genes in Biopsy Samples from Patients with Oral Squamous Cell Carcinoma

open access: yesDiagnostics, 2023
Introduction: MicroRNAs (miRs) are a group of endogenous, non-coding, 18-24 nucleotide length single-strand RNAs that mediate gene expression at the post-transcriptional level through mRNA degradation or translational repression.
A. Garajei   +11 more
semanticscholar   +1 more source

The oncogenic miR-429 promotes triple-negative breast cancer progression by degrading DLC1

open access: yesAging, 2023
Lines of evidence have demonstrated that the oncogenic miRNAs are pivotal to the progression of breast cancer. In this study, we investigated the biological traits of microRNA-429 (miR-429) in triple-negative breast cancer (TNBC) and the underlying ...
Yao Li   +7 more
semanticscholar   +1 more source

Bioinformatic Analysis of miR-200b/429 and Hub Gene Network in Cervical Cancer

open access: yesBiochemical Genetics, 2023
The miR-200b/429 located at 1p36 is a highly conserved miRNA cluster emerging as a critical regulator of cervical cancer. Using publicly available miRNA expression data from TCGA and GEO followed by independent validation, we aimed to identify the ...
Vaibhav Shukla   +5 more
semanticscholar   +1 more source

miR-429 Suppresses Endometrial Cancer Progression and Drug Resistance via DDX53

open access: yesJournal of Personalized Medicine, 2023
(1) Background: To examine miR-429-meditated DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 (DDX53) function in endometrial cancer (EC). (2) Methods: DDX53 and miR-429 levels were measured using quantitative real-time polymerase chain reaction and western ...
Kyung-jun Lee   +11 more
semanticscholar   +1 more source

Upregulated microRNA-429 confers endometrial stromal cell dysfunction by targeting HIF1AN and regulating the HIF1A/VEGF pathway

open access: yesOpen Medicine, 2023
Endometriosis (EM) is a prevalent estrogen-dependent disorder that adversely affects the life quality of many reproductive-age women. Previous evidence has suggested the significant role of miR-429 in EM; however, its molecular mechanisms underlying EM ...
R. Zheng, Yulan Liu, Yan Lei, Yan Yue
semanticscholar   +1 more source

Ginsenoside Rg3 Alleviates Cisplatin Resistance of Gastric Cancer Cells Through Inhibiting SOX2 and the PI3K/Akt/mTOR Signaling Axis by Up-Regulating miR-429

open access: yesFrontiers in Genetics, 2022
Platinum-based cytotoxic chemotherapy is considered the standard treatment for advanced gastric cancer (GC). However, cisplatin chemoresistance often occurs with the mechanisms being not well clarified, which results in the cancer recurrence and poor ...
Xiaofeng Wang   +4 more
semanticscholar   +1 more source

Angiogenesis Driven by the CEBPD–hsa-miR-429–VEGFA Signaling Axis Promotes Urothelial Carcinoma Progression

open access: yesCells, 2022
Background and Purpose: This research aimed to excavate the alternative mechanism of CEBPD on tumor growth and explore the biological significance of the CEBPD/hsa-miR-429/VEGFA axis on angiogenesis in urothelial carcinoma (UC).
T. Chan   +6 more
semanticscholar   +1 more source

miR‐200a/b/‐429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer

open access: yesMolecular Oncology, 2022
Many patients with locally advanced cervical cancer experience recurrence within the radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to identify patients in need of intensified treatment.
A. Nilsen   +10 more
semanticscholar   +1 more source

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