Results 21 to 30 of about 113,627 (49)

Research progress of artificial intelligence in moyamoya disease

Frontiers in Neurology
Moyamoya disease (MMD), a chronic, progressive cerebrovascular disorder of unknown etiology, presents significant diagnostic and therapeutic challenges in clinical practice.
Huimin Huang, Huimin Huang, Ning Zheng, Lei Feng, Shuo Shao   +4 more
doaj   +1 more source

Switch from fingolimod to ozanimod for safety or intolerance reasons

Therapeutic Advances in Neurological Disorders
Introduction: Ozanimod is a new-generation sphingosine-1-phosphate (S1P) modulator, approved for the treatment of multiple sclerosis (MS), offering higher selectivity for S1P receptor 1 and 5 (SPR1-5), minimizing potential safety concerns related to S1P3
Elisabetta Signoriello, Giuseppe Romano, Matteo Foschi, Aurora Zanghì, Emanuele D’Amico, Roberta Fantozzi, Diego Centonze, Giacomo Lus   +7 more
doaj   +1 more source

Sphenopalatine ganglion stimulation for the treatment of trigeminal neuropathic pain

Frontiers in Neurology
IntroductionUnlike idiopathic trigeminal neuralgia, which can be treated with conventional neurosurgical methods such as microvascular decompression, radiofrequency rhizotomy of the Gasser ganglion, or stereotactic radiosurgery, trigeminal neuropathic ...
Paweł Sokal, Sara Kierońska-Siwak, Marcin Rusinek, Magdalena Jabłońska, Antoni Nehring, Oskar Puk, Damian Palus, Renata Jabłońska   +7 more
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Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways

Frontiers in Neurology
ObjectiveTo investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising ...
Jiawei Sun, Yingqi Zhang, Zhifeng Liu, Hanyu Zhang, Jiayue Liu, Yue Xu, Rentuya Na, Hongzheng Zhang, Jiawang Yan, Tianyuan Yu   +9 more
doaj   +1 more source

Early cerebrospinal fluid elevations of pTau-217 in severe traumatic brain injury subjects

Frontiers in Neurology
IntroductionTauopathies, including Alzheimer’s disease (AD), feature abnormal accumulations of hyperphosphorylated Tau protein; however, their biomarker potential in traumatic brain injury (TBI) is not well-defined.
Hamad Yadikar, Firas H. Kobeissy, Firas H. Kobeissy, Firas H. Kobeissy, Firas H. Kobeissy, Firas H. Kobeissy, Claudia Robertson, Spyridoula Tsetsou, John B. Williamson, John B. Williamson, Damon G. Lamb, Damon G. Lamb, Amy K. Wagner, Amy K. Wagner, Amy K. Wagner, Amy K. Wagner, Amy K. Wagner, Todd Kibaugh, Shih-Han Kao, Zhifeng Kou, Zhifeng Kou, Robert D. Welch, Jose-Miguel Yamal, Luis Leon-Novelo, Richard Rubenstein, Richard Rubenstein, Kevin K. W. Wang, Kevin K. W. Wang, Kevin K. W. Wang, Kevin K. W. Wang, Kevin K. W. Wang   +30 more
doaj   +1 more source

Altered neuromagnetic activity under visual stimuli in migraine: a multi-frequency magnetoencephalography study

Frontiers in Neurology
BackgroundMigraine is a chronic neurological disorder associated with a variety of abnormal visual symptoms. However, the mechanisms of visual processing in migraine are not fully understood.
Di Wu, Zhiyuan Zhou, Yingfan Wang, Hongxing Liu, Yuanwen Yu, Qiqi Chen, Xiaoshan Wang   +6 more
doaj   +1 more source

Quantification of rehabilitation for patients with Parkinson’s disease and related disorders using wearable devices; a proof of concept

Frontiers in Neurology
IntroductionTo date, disease-modifying therapies have not been established for Parkinson’s disease (PD) or atypical parkinsonisms. Exercise has been reported to help maintain functional abilities and delay disease progression.
Hikaru Kamo, Hikaru Kamo, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Koichi Nagaki, Koichi Nagaki, Koichi Nagaki, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori   +20 more
doaj   +1 more source

The effect of virtual reality-based treadmill gait training on functional mobility and balance in chronic stroke patients: a randomized controlled trial

Frontiers in Neurology
IntroductionStroke is a leading cause of long-term disability worldwide. Chronic stroke survivors experience gait and balance impairments, limiting mobility and increasing fall risk.
Seung-Hyeon Han, Hyeon Ju Jang, Jong Weon Lee, Jong Weon Lee, Jin Woong Cheong, Young Dae Kim, Hyo Suk Nam, Deog Young Kim, Deog Young Kim   +8 more
doaj   +1 more source

Biomarkers in spinal muscular atrophy

Frontiers in Neurology
Spinal muscular atrophy is a hereditary disorder leading to severe neuromuscular impairment. With the introduction of disease-modifying therapies in recent years, the role of biomarkers has expanded from aiding diagnosis to monitoring treatment responses,
Liping Yan, Jinping Zhang, Jian Zheng, Hua Hao   +3 more
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Biomarkers and therapeutic targets in early Alzheimer’s disease: an Olink proteomics study

Frontiers in Neurology
PurposeThis study aims to analyze differential expression of inflammation-related proteins in plasma from patients with mild cognitive impairment (MCI) and early-stage Alzheimer’s disease (AD), for exploring potential biomarkers and therapeutic targets ...
Jianan Wei, Hui Ni, Weiwei Liu, Hui Xu, Chen Wang, Geng Geng, Zhongwei He, Guofang Chen, Guofang Chen   +8 more
doaj   +1 more source