Results 21 to 30 of about 141,328 (115)

MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis

BMC Molecular and Cell Biology, 2022
Background Hepatocellular carcinoma (HCC) is a common malignancy. Long non-coding RNAs (lncRNAs) partake in the progression of HCC. However, the role of lncRNA MAPKAPK5-AS1 in the development of HCC has not been fully clarified.
Z. Peng, Xin-ping Ouyang, Yexing Wang, Qiming Fan   +3 more
semanticscholar   +1 more source

FV-429 induces autophagy blockage and lysosome-dependent cell death of T-cell malignancies via lysosomal dysregulation

Cell Death and Disease, 2021
It is widely accepted that lysosomes are essential for cell homeostasis, and autophagy plays an important role in tumor development. Here, we found FV-429, a synthetic flavonoid compound, inhibited autophagy flux, promoted autophagosomes accumulation ...
Po Hu, Jubo Wang, Yingjie Qing, Hui Li, Wenzhuo Sun, Xiaoxuan Yu, H. Hui, Qinglong Guo, Jingyan Xu   +8 more
semanticscholar   +1 more source

The decreased expression of miR-429 in plasma exosomes after spinal cord injury inhibits neuronal apoptosis by mediating the PTEN/PI3K/Akt pathway

Annals of Translational Medicine, 2022
Background Neuronal apoptosis after spinal cord injury (SCI) leads to sensorial and motorial dysfunction. Exosomes are vesicles that contain many cellular components, including microRNA, and the role of miR-429 in plasma exosomes in this process after ...
Jiayi Huang, Chunshuai Wu, Guanhua Xu, Yue Sun, Chao Gui, Jiawei Fu, Zhiming Cui, Haiming Huang   +7 more
semanticscholar   +1 more source

Knockdown of circ-PVT1 inhibits the progression of lung adenocarcinoma and enhances the sensitivity to cisplatin via the miR-429/FOXK1 signaling axis

Molecular Medicine Reports, 2021
Lung cancer is one of the most prevalent cancers in China, and its incidence and morbidity remain high due to various independent factors. Lung adenocarcinoma (ADC) is the most common type of non-small cell lung carcinoma.
L. Cao, Xuefeng Zhou, Xi-wei Ding, Dongyun Gao   +3 more
semanticscholar   +1 more source

Circular RNA circRNA_0082835 promotes progression and lymphatic metastasis of primary melanoma by sponging microRNA miRNA-429

Bioengineered, 2021
To identify how circular RNA circRNA_0082835 impacts melanoma cells and lymphatic metastasis to observe whether it exerts effects through its action mechanism of sponging microRNA miR-429. Clinical baseline information was collected, and clinical samples
Yute Sun, Zuoqiong Hou, B. Luo, Chujun Li, Jinfang Liu, Jianlan Liu, Jian Tang, G. Yao   +7 more
semanticscholar   +1 more source

Berberine inhibits the proliferation, invasion and migration of endometrial stromal cells by downregulating miR-429

Molecular Medicine Reports, 2021
Endometriosis (EM) is a common gynecological disease, and its pathological process is accompanied by the migration and proliferation of uterine cells. Berberine (BBR) has been shown to exhibit antitumor activity; however, the effects of BBR on EM have ...
Yongjuan Gu, Zhi-yu Zhou
semanticscholar   +1 more source

circ-0007707/miR-429/PDGFD Pathway Regulates the Progression of Gastric Cancer by Modulating the Immune-Gene Signature

Journal of Oncology, 2022
Background Immunotherapy is an important treatment modality for gastric cancer, therefore, it is crucial to understand the regulators of the tumor microenvironment in gastric cancer.
Yang Yang, Weibiao Kang, Yu Yuan, C. Duan, Wei Chen, Changjun Yu   +5 more
semanticscholar   +1 more source

MicroRNA-429 acts as a tumor suppressor in colorectal cancer by targeting high mobility group box 3

Oncology Letters, 2021
Colorectal cancer (CRC) is one of the most common solid tumors worldwide and has an extremely poor prognosis. MicroRNA-429 (miR-429) has been reported to participate in the progression of CRC.
Xiangyang Tian, Jianlan Chang, Ningning Zhang, Shouxin Wu, Huimin Liu, Junyan Yu   +5 more
semanticscholar   +1 more source

Spectral and type I X-ray burst studies of 4U 1702−429 using AstroSat observations

Monthly notices of the Royal Astronomical Society
4U 1702−429, an atoll-type neutron star low-mass X-ray binary, was observed twice by AstroSat/Soft X-ray Telescope (SXT) and Large Area X-ray Proportional Counters (LAXPC-20) on 2018 April 27 and 2019 August 8. Persistent emission spectra of the source
M. Varun, N. T. Thomas, S. B. Gudennavar, S. G. Bubbly   +3 more
semanticscholar   +1 more source

HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis

Molecular Therapy: Nucleic Acids, 2021
Despite the increasing prevalence of fatty liver diseases worldwide, the molecular mechanism underlying their pathogenesis remains poorly defined. This study examines the expression and significance of tumor necrosis factor (TNF) receptor-associated ...
Zhi Zhang, Huiqing Wen, Bangjian Peng, Jun Weng, Fanhong Zeng   +4 more
semanticscholar   +1 more source