Results 51 to 60 of about 141,328 (115)

Chinese massage therapy (Tuina) inhibits motor neuron apoptosis in rats with sciatic nerve injury by regulating the cPLA2 and RhoA/ROCK2 signaling pathways

Frontiers in Neurology
ObjectiveTo investigate whether Tuina therapy alleviated inflammation and motor neuron apoptosis in sciatic nerve injury (SNI) rats by regulating cytosolic phospholipase A2 (cPLA2) and Ras homolog family member A/Rho-associated coiled-coil comprising ...
Jiawei Sun, Yingqi Zhang, Zhifeng Liu, Hanyu Zhang, Jiayue Liu, Yue Xu, Rentuya Na, Hongzheng Zhang, Jiawang Yan, Tianyuan Yu   +9 more
doaj   +1 more source

Early cerebrospinal fluid elevations of pTau-217 in severe traumatic brain injury subjects

Frontiers in Neurology
IntroductionTauopathies, including Alzheimer’s disease (AD), feature abnormal accumulations of hyperphosphorylated Tau protein; however, their biomarker potential in traumatic brain injury (TBI) is not well-defined.
Hamad Yadikar, Firas H. Kobeissy, Firas H. Kobeissy, Firas H. Kobeissy, Firas H. Kobeissy, Firas H. Kobeissy, Claudia Robertson, Spyridoula Tsetsou, John B. Williamson, John B. Williamson, Damon G. Lamb, Damon G. Lamb, Amy K. Wagner, Amy K. Wagner, Amy K. Wagner, Amy K. Wagner, Amy K. Wagner, Todd Kibaugh, Shih-Han Kao, Zhifeng Kou, Zhifeng Kou, Robert D. Welch, Jose-Miguel Yamal, Luis Leon-Novelo, Richard Rubenstein, Richard Rubenstein, Kevin K. W. Wang, Kevin K. W. Wang, Kevin K. W. Wang, Kevin K. W. Wang, Kevin K. W. Wang   +30 more
doaj   +1 more source

Altered neuromagnetic activity under visual stimuli in migraine: a multi-frequency magnetoencephalography study

Frontiers in Neurology
BackgroundMigraine is a chronic neurological disorder associated with a variety of abnormal visual symptoms. However, the mechanisms of visual processing in migraine are not fully understood.
Di Wu, Zhiyuan Zhou, Yingfan Wang, Hongxing Liu, Yuanwen Yu, Qiqi Chen, Xiaoshan Wang   +6 more
doaj   +1 more source

Quantification of rehabilitation for patients with Parkinson’s disease and related disorders using wearable devices; a proof of concept

Frontiers in Neurology
IntroductionTo date, disease-modifying therapies have not been established for Parkinson’s disease (PD) or atypical parkinsonisms. Exercise has been reported to help maintain functional abilities and delay disease progression.
Hikaru Kamo, Hikaru Kamo, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Genko Oyama, Koichi Nagaki, Koichi Nagaki, Koichi Nagaki, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori, Nobutaka Hattori   +20 more
doaj   +1 more source

miR-429 as biomarker for diagnosis, treatment and prognosis of cancers and its potential action mechanisms: A systematic literature review.

Neoplasma (Bratislava), 2019
miR-429 is a member of miR-200 family. Accumulated evidence has indicated that miR-429 dysregulation is involved in the epithelial-mesenchymal transition (EMT), progression, development, invasion, metastasis, apoptosis and drug resistance of a variety of
Chunmei Guo, Shuqing Liu, Ming-Zhong Sun
semanticscholar   +1 more source

The effect of virtual reality-based treadmill gait training on functional mobility and balance in chronic stroke patients: a randomized controlled trial

Frontiers in Neurology
IntroductionStroke is a leading cause of long-term disability worldwide. Chronic stroke survivors experience gait and balance impairments, limiting mobility and increasing fall risk.
Seung-Hyeon Han, Hyeon Ju Jang, Jong Weon Lee, Jong Weon Lee, Jin Woong Cheong, Young Dae Kim, Hyo Suk Nam, Deog Young Kim, Deog Young Kim   +8 more
doaj   +1 more source

Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis

Molecular Therapy: Nucleic Acids, 2019
The anti-angiogenic treatment of malignant glioma cells is an effective method to treat high-grade gliomas. However, due to the presence of vasculogenic mimicry (VM), the anti-angiogenic treatment of gliomas is not significantly effective in improving ...
Di Wang, Jian Zheng, Xiaobai Liu, Yixue Xue, Libo Liu, Jun Ma, Qianru He, Zhen Li, H. Cai, Yunhui Liu   +9 more
semanticscholar   +1 more source

Biomarkers in spinal muscular atrophy

Frontiers in Neurology
Spinal muscular atrophy is a hereditary disorder leading to severe neuromuscular impairment. With the introduction of disease-modifying therapies in recent years, the role of biomarkers has expanded from aiding diagnosis to monitoring treatment responses,
Liping Yan, Jinping Zhang, Jian Zheng, Hua Hao   +3 more
doaj   +1 more source

Biomarkers and therapeutic targets in early Alzheimer’s disease: an Olink proteomics study

Frontiers in Neurology
PurposeThis study aims to analyze differential expression of inflammation-related proteins in plasma from patients with mild cognitive impairment (MCI) and early-stage Alzheimer’s disease (AD), for exploring potential biomarkers and therapeutic targets ...
Jianan Wei, Hui Ni, Weiwei Liu, Hui Xu, Chen Wang, Geng Geng, Zhongwei He, Guofang Chen, Guofang Chen   +8 more
doaj   +1 more source

The effect of rTMS intervention with different targets on neural remodeling in stroke patients: a randomized controlled trial

Frontiers in Neurology
BackgroundrTMS is widely used to improve motor function in patients with ischemic stroke, but there are few studies on different targets. In order to develop a clinical precision rehabilitation program, this study aims to explore the effects of rTMS at ...
Li Zhao, Li Chen, Qiu Wang, Xinyi Li, Sha Li, Chunxiao Wan   +5 more
doaj   +1 more source