Results 11 to 20 of about 88,963 (266)
Cells, 2021 In human cells, each rDNA unit consists of the ~13 kb long ribosomal part and ~30 kb long intergenic spacer (IGS). The ribosomal part, transcribed by RNA polymerase I (pol I), includes genes coding for 18S, 5.8S, and 28S RNAs of the ribosomal particles, as well as their four transcribed spacers.
Evgeny Smirnov +2 more
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Variability of Human rDNA [PDF]
Cells, 2021 In human cells, ribosomal DNA (rDNA) is arranged in ten clusters of multiple tandem repeats. Each repeat is usually described as consisting of two parts: the 13 kb long ribosomal part, containing three genes coding for 18S, 5.8S and 28S RNAs of the ribosomal particles, and the 30 kb long intergenic spacer (IGS).
Evgeny Smirnov +4 more
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Establishment of a genome editing system and expression of heterologous proteins in the nonconventional yeast <i>Pichia kudriavzevii</i>. [PDF]
mLifemLife, EarlyView.
Ma J, Cui Y, Yin B, Jin C.
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Calorie restriction reduces rDNA recombination independently of rDNA silencing [PDF]
Aging Cell, 2009 SummaryCalorie restriction (CR) extends lifespan in yeast, worms, flies and mammals, suggesting that it acts via a conserved mechanism. In yeast, activation of the NAD‐dependent histone deacetylase, Sir2, by CR is thought to increase silencing at the ribosomal DNA, thereby reducing the recombination‐induced generation of extrachromosomal rDNA circles ...
Riesen, Michèle, Morgan, Alan
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Quelling targets the rDNA locus and functions in rDNA copy number control [PDF]
BMC Microbiology, 2009 RNA silencing occurs in a broad range of organisms. Although its ancestral function is probably related to the genome defense mechanism against repetitive selfish elements, it has been found that RNA silencing regulates different cellular processes such as gene expression and chromosomal segregation.
Germano Cecere, COGONI, Carlo
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Complete deletion of yeast chromosomal rDNA repeats and integration of a new rDNA repeat: use of rDNA deletion strains for functional analysis of rDNA promoter elements in vivo [PDF]
Nucleic Acids Research, 2000 Strains of Saccharomyces cerevisiae were constructed in which chromosomal rDNA repeats are completely deleted and their growth is supported by a plasmid carrying a single rDNA repeat, either a plasmid carrying the 35S rRNA gene transcribed from the native promoter by RNA polymerase I or a plasmid carrying the 35S rRNA gene fused to the GAL7 promoter ...
Wai, Hobert H. +3 more
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Allelic inactivation of rDNA loci [PDF]
Genes & Development, 2009 Human cells contain several hundred ribosomal genes (rDNA) that are clustered into nucleolar organizer regions (NORs) on the short arms of five different acrocentric chromosomes. Only ∼50% of the gene copies are actually expressed in somatic cells. Here, we used a new cytological technique to demonstrate that rDNA is regulated allelically in a regional
Sharon, Schlesinger +3 more
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Cytogenetic variability among Bradyporinae species (Orthoptera: Tettigoniidae)
European Journal of Entomology, 2013 Chromosomes of six European species (one with two subspecies) of Orthoptera belonging to the tribes Ephippigerini and Bradyporini were analyzed using C-banding, Ag-NOR, DAPI (AT-rich)/CMA3 (GC-rich) staining and fluorescence in situ hybridization (FISH ...
Elżbieta WARCHAŁOWSKA-ŚLIWA +5 more
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Microorganisms, 2019 Metabarcoding and high-throughput sequencing methods have greatly improved our understanding of protist diversity. Although the V4 region of small subunit ribosomal DNA (SSU-V4 rDNA) is the most widely used marker in DNA metabarcoding of eukaryotic ...
Zifeng Zhan, Ju Li, Kuidong Xu
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Morphology and rDNA phylogeny of a Mediterranean Coolia monotis (Dinophyceae) strain from Greece
Scientia Marina, 2006 Sequences of LSU and SSU ribosomal RNA genes and phylogeny have not been widely investigated for the dinoflagellate Coolia monotis Meunier, and no information is available on the small and large rDNA subunits of Mediterranean strains.
Nicolas P. Dolapsakis +3 more
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