Results 31 to 40 of about 93,372 (292)

Meloidogyne paramali n. sp. (Nematoda: Meloidogyninae) and First Report of M. marylandi in maple and yacca tree from Japan

Journal of Nematology, 2023
Meloidogyne paramali n. sp. was detected from Japanese maple trees (Acer palmatum) from Chiba, Japan during quarantine inspections in China. This species is characterized by second-stage juveniles (J2) with short tail length 32.2 (24–36.8) μm, finely ...
Gu Jianfeng, Fang Yiwu, Ma Xinxin, Shao Baolin, Zhuo Kan   +4 more
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

First molecular observation on Mylonchulus hawaiiensis from South Africa

Helminthologia
During a survey of soil nematodes in South Africa, a species of predatory nematodes, namely Mylonchulus hawaiiensis was recovered from soil in the Magoebaskloof mountain of Limpopo Province, South Africa.
Shokoohi E.
doaj   +1 more source

Complete deletion of yeast chromosomal rDNA repeats and integration of a new rDNA repeat: use of rDNA deletion strains for functional analysis of rDNA promoter elements in vivo [PDF]

Nucleic Acids Research, 2000
Strains of Saccharomyces cerevisiae were constructed in which chromosomal rDNA repeats are completely deleted and their growth is supported by a plasmid carrying a single rDNA repeat, either a plasmid carrying the 35S rRNA gene transcribed from the native promoter by RNA polymerase I or a plasmid carrying the 35S rRNA gene fused to the GAL7 promoter ...
Wai, Hobert H., Vu, Loan, Oakes, Melanie, Nomura, Masayasu   +3 more
openaire   +3 more sources

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Copy Number Variations of Human Ribosomal Genes in Health and Disease: Role and Causes

Frontiers in Bioscience-Landmark
Background: A number of association studies have linked ribosomal DNA gene copy number (rDNA CN) to aging and pathology. Data from these studies are contradictory and depend on the quantitative method.
Natalia N. Veiko, Elizaveta S. Ershova, Elena I. Kondratyeva, Lev N. Porokhovnik, Rena A. Zinchenko, Yuliya L. Melyanovskaya, Stanislav A. Krasovskiy, Tatiana P. Vasilyeva, George P. Kostyuk, Natalia V. Zakharova, Svetlana V. Kostyuk   +10 more
doaj   +1 more source

Metronidazole‐Loaded Cyclodextrin Nanogels for Antibacterial Therapy and Microbiota Regulation in Periodontitis

Advanced Healthcare Materials, EarlyView.
A methacrylamide β‐cyclodextrin‐based nanogel (MACD nGel) is developed to load the antimicrobial drug Metronidazole (MNZ) for topical delivery for the treatment of periodontitis. It is demonstrated that cyclodextrin nanogel (nGel) loaded with metronidazole provides an efficient drug delivery route but also has potential clinical applications and offers
Yanjing Ji, Ruichen Zhang, Dongyi Xu, Patrick C. A. van der Wel, Alessia Lasorsa, Guotai Li, Fangze Guo, Qihui Zhou, Patrick van Rijn   +8 more
wiley   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Silver-negative NORs in Pamphagus ortolaniae (Orthoptera: Pamphagidae)

European Journal of Entomology, 2008
The present paper reports some cytogenetic peculiarities observed in the Ag-NORs of Pamphagus ortolaniae chromosomes, the unusual behaviour of ribosomal sites after silver staining and the intense Ag-positive reaction of centromeric regions at ...
Roberto VITTURI, Antonella LANNINO, Caterina MANSUETO, Valentina MANSUETO, Mariastella COLOMBA   +4 more
doaj   +1 more source