Results 91 to 100 of about 1,906,154 (308)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Reaching the Rural Audience [PDF]
, 1983 Measuring radio\u27s effectiveness at reaching rural audiences has been the subject of hundreds of studies over the past 50 ...
Mangan, Frank J., Frank J. Mangan
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Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Aliquot sequence 3630 ends after reaching 100 digits [PDF]
, 2002 Article dans revue scientifique avec comité de lecture.In this paper we present a new computational record: the aliquot sequence starting at $3630$ converges to~$1$ after reaching a hundred decimal digits.
Zimmermann, P. +4 more
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Optimal control of reaching is disturbed in complex regional pain syndrome: a single-case study
, 2017 Michihiro Osumi,1 Masahiko Sumitani,2 Shin-ichiro Kumagaya,3 Shu Morioka1 1Neurorehabilitation Research Center, Kio University, Nara, 2Department of Pain and Palliative Medicine, The University of Tokyo Hospital, 3Research Center for Advanced Science and
Sumitani M +3 more
core
Challenges for improving consensus reaching process in collective decisions
, 2007 The majority rule is frequently presented as a cornerstone of any democratic society, guiding many group decision-making processes where final decision requires the agreement of more than half the people involved.
Martínez, L. +1 more
core +1 more source