Results 101 to 110 of about 4,532,035 (362)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Neural Correlates of Learning and Trajectory Planning in the Posterior Parietal Cortex
Frontiers in Integrative Neuroscience, 2013 The posterior parietal cortex (PPC) is thought to play an important role in the planning of visually-guided reaching movements. However, the relative roles of the various subdivisions of the PPC in this function are still poorly understood.
Elizabeth B Torres +3 more
doaj +1 more source
Maximising Survival, Growth, and Goal Reaching Under Borrowing Constraints [PDF]
, 2012 In this paper, we consider three problems related to survival, growth, and goal reaching maximization of an investment portfolio with proportional net cash flow. We solve the problems in a market constrained due to borrowing prohibition.
Yener, Haluk
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Failure of the Airway Scope to reach the larynx [PDF]
, 2007 Nobuko Sasano +2 more
openalex +1 more source
Supernova Remnant 1987A: Opening the Future by Reaching the Past
, 2005 We report an up-turn in the soft X-ray light curve of supernova remnant (SNR) 1987A in late 2003 (~6200 days after the explosion), as observed with the Chandra X-ray Observatory.
David N. Burrows +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Reaching Out: Board Ambassadors for Growth in Community Foundations [PDF]
, 2011 Outlines how community foundations can maximize trustees' roles in building relationships, visibility, and credibility in the community by providing clear expectations, continuous education, equipment, positive experiences, and a supportive ...
core
Reaching Out to the Faculty: Providing Subject-Specific Academic Resources
, 2007 Library journals frequently have articles emphasizing the large gulf that seems to exist between academic librarians and teaching faculty members.1 Librarians view this divide as a serious problem and have suggested different strategies to overcome it ...
Jaeger, John
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source